iPTMnet Report for Q96A00 (PPP1R14A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96A00 / PP14A_HUMAN
Protein Name Protein phosphatase 1 regulatory subunit 14A
Gene Name Name: PPP1R14A
Synonyms:CPI17,PPP1INL;
Organism Homo sapiens (Human)

PRO ID PR:Q96A00
DAG View
PRO Name protein phosphatase 1 regulatory subunit 14A (human)
Definition A protein phosphatase 1 regulatory subunit 14A that is encoded in the genome of human.
Short Label hPPP1R14A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96A00 (PPP1R14A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R5 Methylation PhosphoSitePlus
S12 Phosphorylation O43293 (DAPK3) phospho.ELM   PhosphoSitePlus   RLIMS-P 11287002, 23541585
S16 Phosphorylation PhosphoSitePlus
R19 Methylation PhosphoSitePlus
R21 Methylation PhosphoSitePlus
S26 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18088087
K32 Methylation PhosphoSitePlus
T38 Phosphorylation Q05655 (PRKCD) , P17612 (PRKACA) , O75116 (ROCK2) , Q02156 (PRKCE) , O43293 (DAPK3) , Q15139 (PRKD1) , Q13976 (PRKG1) , P17252 (PRKCA) , Q13418 (ILK) , Q05513 (PRKCZ) , Q13153 (PAK1) , P98161 (PKD1) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 15184667, 15003508, 10744661, ...12030846, 16472257, 35418530, 18835557, 32471307, 12359219, 25980620, 15665049, 12804574, 11517233, 11943207, 12595264, 11287002, 11734001, 12604330, 10869555, 12144526, 10924361, 17200564
K40 Methylation PhosphoSitePlus
S128 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 18088087, 23186163, 12604330
S130 Phosphorylation Q9UQM7 (CAMK2A) phospho.ELM   PhosphoSitePlus   RLIMS-P 12604330
S134 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18088087, 23186163
S136 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 21406692, 18088087
Site PTM Type PTM Enzyme Score Source PMID
S26 Phosphorylation HPRD 19651622, 18088087
T38 Phosphorylation P17252 (PRKCA) , Q05513 (PRKCZ) , Q02156 (PRKCE) , Q15139 (PRKD1) HPRD 15003508
S128 Phosphorylation HPRD 19413330, 19651622, 18088087, ...20068231
S130 Phosphorylation HPRD 19651622, 20068231
S134 Phosphorylation HPRD 19413330, 18088087, 20068231
S136 Phosphorylation HPRD 19413330, 19651622, 18088087
Site PTM Type PTM Enzyme Score Source PMID
Y64 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R21 C21 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y64 C64 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S136 N136 Biomuta DOID:1324 / lung cancer [ cosmic ]