iPTMnet Report for Q969X5 (ERGIC1)
Protein Information
| UniProt AC / UniProt ID | Q969X5 / ERGI1_HUMAN |
| Protein Name | Endoplasmic reticulum-Golgi intermediate compartment protein 1 |
| Gene Name | Name: ERGIC1 Synonyms:ERGIC32,KIAA1181;ORFNames:HT034; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q969X5 |
| PRO Name | endoplasmic reticulum-Golgi intermediate compartment protein 1 (human) |
| Definition | An endoplasmic reticulum-Golgi intermediate compartment protein 1 that is encoded in the genome of human. |
| Short Label | hERGIC1 |
| Category | organism-gene |
Q969X5 (ERGIC1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| Y11 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N74 | N-Glycosylation | score4 | GlyGen UniProt | 15308636, 19159218 | ||
| C115 | Methylation | score1 | IEDB | 31844290 | ||
| T138 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| Y187 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K190 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y196 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K199 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y209 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y216 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y219 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S236 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K241 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K288 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| C115 | F115 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| C115 | S115 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
| Y196 | * | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
| Y209 | C209 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |
DAG View