iPTMnet Report for Q969V5 (MUL1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q969V5 / MUL1_HUMAN
Protein Name Mitochondrial ubiquitin ligase activator of NFKB 1
Gene Name Name: MUL1
Synonyms:C1orf166,GIDE,MAPL,MULAN,RNF218;
Organism Homo sapiens (Human)

PRO ID PR:Q969V5
DAG View
PRO Name mitochondrial ubiquitin ligase activator of NFKB 1 (human)
Definition A mitochondrial ubiquitin ligase activator of NFKB 1 that is encoded in the genome of human.
Short Label hMUL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q969V5 (MUL1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Ubiquitination PRO
S3 Phosphorylation PhosphoSitePlus
K44 Ubiquitination PhosphoSitePlus
K52 Ubiquitination PhosphoSitePlus   UniProt 25621951
K76 Ubiquitination PhosphoSitePlus
K88 Ubiquitination PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
K143 Ubiquitination PhosphoSitePlus
Y156 Phosphorylation PhosphoSitePlus
K214 Ubiquitination PhosphoSitePlus
K273 Ubiquitination PhosphoSitePlus   UniProt 25621951
K291 Ubiquitination PhosphoSitePlus
K299 Ubiquitination PhosphoSitePlus   UniProt 25621951
S311 Phosphorylation PhosphoSitePlus
Y350 Phosphorylation PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048487 (hMUL1/UbiqLys+) ub PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y156 H156 Biomuta DOID:1319 / brain cancer [ cosmic ]
K214 E214 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K273 R273 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]