iPTMnet Report for Q969S9 (GFM2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q969S9 / RRF2M_HUMAN
Protein Name Ribosome-releasing factor 2, mitochondrial
Gene Name Name: GFM2
Synonyms:EFG2;ORFNames:MSTP027;
Organism Homo sapiens (Human)

PRO ID PR:Q969S9
DAG View
PRO Name ribosome-releasing factor 2, mitochondrial (human)
Definition An elongation factor G 2, mitochondrial that is encoded in the genome of human.
Short Label hGFM2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q969S9 (GFM2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S11 Phosphorylation PhosphoSitePlus
T14 Phosphorylation PhosphoSitePlus
S31 Phosphorylation PhosphoSitePlus
K196 Ubiquitination PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
K205 Ubiquitination PhosphoSitePlus
K218 Ubiquitination PhosphoSitePlus
K230 Ubiquitination PhosphoSitePlus
K233 Acetylation PhosphoSitePlus
K243 Ubiquitination PhosphoSitePlus
K259 Ubiquitination PhosphoSitePlus
K271 Acetylation PhosphoSitePlus
Y348 Phosphorylation PhosphoSitePlus
K373 Ubiquitination PhosphoSitePlus
K394 Ubiquitination PhosphoSitePlus
S426 Phosphorylation PhosphoSitePlus
K451 Ubiquitination PhosphoSitePlus
K510 Ubiquitination PhosphoSitePlus
K520 Ubiquitination PhosphoSitePlus
Y556 Phosphorylation PhosphoSitePlus
Y564 Phosphorylation PhosphoSitePlus
Y611 Phosphorylation PhosphoSitePlus
S614 Phosphorylation PhosphoSitePlus
Y700 Phosphorylation PhosphoSitePlus
S702 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K196 N196 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
K199 T199 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K259 N259 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S426 A426 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
Y611 D611 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y700 C700 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:4159 / skin cancer [ cosmic ]