iPTMnet Report for Q969R2 (OSBP2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q969R2 / OSBP2_HUMAN
Protein Name Oxysterol-binding protein 2
Gene Name Name: OSBP2
Synonyms:KIAA1664,ORP4,OSBPL4;
Organism Homo sapiens (Human)

PRO ID PR:Q969R2
DAG View
PRO Name oxysterol-binding protein 2 (human)
Definition An oxysterol-binding protein 2 that is encoded in the genome of human.
Short Label hOSBP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q969R2 (OSBP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S8 Phosphorylation PhosphoSitePlus
R9 Methylation PhosphoSitePlus
S108 Phosphorylation PhosphoSitePlus
S110 Phosphorylation PhosphoSitePlus
T120 Phosphorylation PhosphoSitePlus
T223 Phosphorylation PhosphoSitePlus
S284 Phosphorylation PhosphoSitePlus
S287 Phosphorylation PhosphoSitePlus
T294 Phosphorylation PhosphoSitePlus
S364 Phosphorylation PhosphoSitePlus
S428 Phosphorylation PhosphoSitePlus
T438 Phosphorylation PhosphoSitePlus
S444 Phosphorylation PhosphoSitePlus
S473 Phosphorylation PhosphoSitePlus
S488 Phosphorylation PhosphoSitePlus
S498 Phosphorylation PhosphoSitePlus
K502 Ubiquitination PhosphoSitePlus
S619 Phosphorylation PhosphoSitePlus
S625 Phosphorylation PhosphoSitePlus
S682 Phosphorylation PhosphoSitePlus
T683 Phosphorylation PhosphoSitePlus
S684 Phosphorylation PhosphoSitePlus
T685 Phosphorylation PhosphoSitePlus
K730 Ubiquitination PhosphoSitePlus
S762 Phosphorylation PhosphoSitePlus
S763 Phosphorylation PhosphoSitePlus   UniProt 23186163
S765 Phosphorylation PhosphoSitePlus
S766 Phosphorylation PhosphoSitePlus
S768 Phosphorylation PhosphoSitePlus
K841 Ubiquitination PhosphoSitePlus
S851 Phosphorylation PhosphoSitePlus
K883 Ubiquitination PhosphoSitePlus
Y900 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y722 Phosphorylation HPRD 20068231
S766 Phosphorylation HPRD 19651622


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T120 I120 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T223 M223 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:363 / uterine cancer [ cosmic, icgc ]
S287 F287 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S473 N473 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S498 L498 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S619 F619 Biomuta DOID:4159 / skin cancer [ cosmic ]
T685 N685 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]