iPTMnet Report for Q969G3 (SMARCE1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q969G3 / SMCE1_HUMAN
Protein Name SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
Gene Name Name: SMARCE1
Synonyms:BAF57;
Organism Homo sapiens (Human)

PRO ID PR:Q969G3
DAG View
PRO Name SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (human)
Definition A SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 that is encoded in the genome of human.
Short Label hSMARCE1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q969G3 (SMARCE1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K3 Acetylation PhosphoSitePlus
K3 Methylation PhosphoSitePlus
R4 Methylation PhosphoSitePlus   UniProt 24129315
S6 Phosphorylation PhosphoSitePlus
Y7 Phosphorylation PhosphoSitePlus
T12 Phosphorylation PhosphoSitePlus
T17 Phosphorylation PhosphoSitePlus
S21 Phosphorylation PhosphoSitePlus
T22 Phosphorylation PhosphoSitePlus
Y28 Phosphorylation PhosphoSitePlus
Y31 Phosphorylation PhosphoSitePlus
S32 Phosphorylation PhosphoSitePlus
R40 Methylation PhosphoSitePlus   UniProt 24129315
T47 Phosphorylation PhosphoSitePlus
T58 Phosphorylation PhosphoSitePlus
K68 Acetylation IEDB 34357683
Y73 Phosphorylation PhosphoSitePlus
K85 Ubiquitination PhosphoSitePlus
K92 Sumoylation PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
K98 Ubiquitination PhosphoSitePlus
K112 Ubiquitination PhosphoSitePlus
Y115 Phosphorylation PhosphoSitePlus
K131 Ubiquitination PhosphoSitePlus
S136 Phosphorylation PhosphoSitePlus
Y139 Phosphorylation PhosphoSitePlus
Y142 Phosphorylation PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
S157 Phosphorylation PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
Y170 Phosphorylation PhosphoSitePlus
K189 Ubiquitination PhosphoSitePlus
T191 Phosphorylation PhosphoSitePlus
T193 Phosphorylation PhosphoSitePlus
S204 Phosphorylation PhosphoSitePlus
K228 Methylation PhosphoSitePlus
K240 Ubiquitination PhosphoSitePlus
K258 Ubiquitination PhosphoSitePlus
T263 Phosphorylation PhosphoSitePlus
S265 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
K271 Ubiquitination PhosphoSitePlus
C274 Methylation IEDB 31844290
K277 Sumoylation PhosphoSitePlus
K277 Ubiquitination PhosphoSitePlus
K284 Ubiquitination PhosphoSitePlus
S314 Phosphorylation PhosphoSitePlus
S317 Phosphorylation PhosphoSitePlus
K328 Acetylation PhosphoSitePlus
K328 Ubiquitination PhosphoSitePlus
T350 Phosphorylation PhosphoSitePlus
S353 Phosphorylation PhosphoSitePlus
S362 Phosphorylation PhosphoSitePlus
T363 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S55 Phosphorylation HPRD 20068231
T58 Phosphorylation HPRD 20068231
S157 Phosphorylation HPRD 20068231
Y182 Phosphorylation HPRD 18767875
S187 Phosphorylation HPRD 18767875
S314 Phosphorylation HPRD 20068231
T363 Phosphorylation HPRD 20068231, 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S6 F6 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
T58 M58 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y73 C73 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ]
S157 I157 Biomuta DOID:1612 / breast cancer [ cosmic ]
K189 N189 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S265 * Biomuta DOID:1612 / breast cancer [ cosmic ]
S314 N314 Biomuta DOID:3571 / liver cancer [ cosmic ]
S353 N353 Biomuta DOID:1324 / lung cancer [ cosmic ]
S362 C362 Biomuta DOID:4362 / cervical cancer [ cosmic ]