iPTMnet Report for Q969F9 (HPS3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q969F9 / HPS3_HUMAN
Protein Name BLOC-2 complex member HPS3
Gene Name Name: HPS3
Organism Homo sapiens (Human)

PRO ID PR:Q969F9
DAG View
PRO Name BLOC-2 complex member HPS3 (human)
Definition A BLOC-2 complex member HPS3 that is encoded in the genome of human.
Short Label hHPS3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q969F9 (HPS3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y5 Phosphorylation PhosphoSitePlus
K19 Ubiquitination PhosphoSitePlus
C52 Methylation IEDB 31844290
K227 Ubiquitination PhosphoSitePlus
K256 Ubiquitination PhosphoSitePlus
K283 Acetylation PhosphoSitePlus
K283 Ubiquitination PhosphoSitePlus
K285 Acetylation PhosphoSitePlus
K285 Ubiquitination PhosphoSitePlus
S303 Phosphorylation PhosphoSitePlus
Y304 Phosphorylation PhosphoSitePlus
S307 Phosphorylation PhosphoSitePlus
K331 Ubiquitination PhosphoSitePlus
S462 Phosphorylation PhosphoSitePlus
S468 Phosphorylation PhosphoSitePlus
T472 Phosphorylation PhosphoSitePlus
S473 Phosphorylation PhosphoSitePlus
K511 Acetylation PhosphoSitePlus
K511 Ubiquitination PhosphoSitePlus
K544 Ubiquitination PhosphoSitePlus
K552 Ubiquitination PhosphoSitePlus
K578 Ubiquitination PhosphoSitePlus
K601 Ubiquitination PhosphoSitePlus
S648 Phosphorylation PhosphoSitePlus
S650 Phosphorylation PhosphoSitePlus
K686 Ubiquitination PhosphoSitePlus
K721 Ubiquitination PhosphoSitePlus
K750 Ubiquitination PhosphoSitePlus
K753 Ubiquitination PhosphoSitePlus
K902 Ubiquitination PhosphoSitePlus
K928 Ubiquitination PhosphoSitePlus
K938 Ubiquitination PhosphoSitePlus
Y957 Phosphorylation PhosphoSitePlus
S960 Phosphorylation PhosphoSitePlus
Y996 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S303 Phosphorylation HPRD 18452278
Y304 Phosphorylation HPRD 18452278
S307 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S468 L468 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
S468 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
T472 I472 Biomuta DOID:363 / uterine cancer [ icgc ]
K552 R552 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K753 R753 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S960 L960 Biomuta DOID:4159 / skin cancer [ cosmic ]