iPTMnet Report for Q93100 (PHKB)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q93100 / KPBB_HUMAN
Protein Name Phosphorylase b kinase regulatory subunit beta
Gene Name Name: PHKB
Organism Homo sapiens (Human)

PRO ID PR:Q93100
DAG View
PRO Name phosphorylase b kinase regulatory subunit beta (human)
Definition A phosphorylase b kinase regulatory subunit beta that is encoded in the genome of human.
Short Label hPHKB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q93100 (PHKB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 20068231
A4 Phosphorylation UniProt 20068231
S27 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 24275569
Y29 Phosphorylation PhosphoSitePlus
K33 Ubiquitination PhosphoSitePlus
S34 Phosphorylation PhosphoSitePlus
K74 Ubiquitination PhosphoSitePlus
Y213 Phosphorylation IEDB 32387766
K226 Ubiquitination PhosphoSitePlus
S314 Phosphorylation PhosphoSitePlus
T316 Phosphorylation PhosphoSitePlus
Y338 Phosphorylation PhosphoSitePlus
K351 Ubiquitination PhosphoSitePlus
Y388 Phosphorylation PhosphoSitePlus
T393 Phosphorylation PhosphoSitePlus
K408 Ubiquitination PhosphoSitePlus
K421 Ubiquitination PhosphoSitePlus
S460 Phosphorylation PhosphoSitePlus
K462 Ubiquitination PhosphoSitePlus
K474 Ubiquitination PhosphoSitePlus
S684 Phosphorylation PhosphoSitePlus
S694 Phosphorylation PhosphoSitePlus
S700 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S701 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T702 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 15302935
S704 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K758 Ubiquitination PhosphoSitePlus
R944 Methylation PhosphoSitePlus
K1037 Ubiquitination PhosphoSitePlus
K1043 Acetylation PhosphoSitePlus
K1047 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T8 Phosphorylation HPRD 20068231
S12 Phosphorylation HPRD 20068231
S27 Phosphorylation HPRD 20166139, 18669648
Y29 Phosphorylation HPRD 18691976
S700 Phosphorylation HPRD 18691976, 18669648, 20058876, ...20068231
S701 Phosphorylation HPRD 18691976, 18669648, 20058876
T702 Phosphorylation HPRD 18691976, 18669648, 20058876, ...20068231
S704 Phosphorylation HPRD 19651622, 18669648, 20058876
Site PTM Type PTM Enzyme Score Source PMID
S694 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation HPRD 20068231
S10 Phosphorylation HPRD 20068231
S12 Phosphorylation HPRD 20068231
S20 Phosphorylation HPRD 20166139, 18669648
Y22 Phosphorylation HPRD 18691976
S693 Phosphorylation HPRD 18691976, 18669648, 20058876, ...20068231
S694 Phosphorylation HPRD 18691976, 18669648, 20058876
T695 Phosphorylation HPRD 18691976, 18669648, 20058876, ...20068231
S697 Phosphorylation HPRD 19651622, 18669648, 20058876


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S10 C10 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S12 N12 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S34 I34 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S314 R314 Biomuta DOID:184 / bone cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic, icgc ]
T316 R316 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y388 C388 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K421 I421 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
S460 I460 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K474 E474 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S684 N684 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S694 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S697 G697 Biomuta DOID:363 / uterine cancer [ cosmic ]
S704 G704 Biomuta DOID:363 / uterine cancer [ cosmic ]
R944 Q944 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]