iPTMnet Report for Q93086 (P2RX5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q93086 / P2RX5_HUMAN
Protein Name P2X purinoceptor 5
Gene Name Name: P2RX5
Synonyms:P2X5;
Organism Homo sapiens (Human)

PRO ID PR:Q93086
DAG View
PRO Name P2X purinoceptor 5 (human)
Definition A P2X purinoceptor 5 that is encoded in the genome of human.
Short Label hP2RX5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q93086 (P2RX5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K20 Ubiquitination PhosphoSitePlus
K53 Ubiquitination PhosphoSitePlus
Y55 Phosphorylation PhosphoSitePlus
T60 Phosphorylation PhosphoSitePlus
S61 Phosphorylation PhosphoSitePlus
K69 Ubiquitination PhosphoSitePlus
N77 N-Glycosylation GlyGen 24190977
K148 Ubiquitination PhosphoSitePlus
K193 Ubiquitination PhosphoSitePlus
N202 N-Glycosylation GlyGen 24190977
K205 Ubiquitination PhosphoSitePlus
K212 Ubiquitination PhosphoSitePlus
K218 Methylation PhosphoSitePlus
K218 Ubiquitination PhosphoSitePlus
C220 Methylation IEDB 31844290
K225 Ubiquitination PhosphoSitePlus
C272 Methylation IEDB 31844290
K284 Ubiquitination PhosphoSitePlus
K287 Ubiquitination PhosphoSitePlus
K327 Acetylation PhosphoSitePlus
S403 Phosphorylation PhosphoSitePlus
S404 Phosphorylation PhosphoSitePlus
N408 N-Glycosylation GlyGen 24190977
S410 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y55 Phosphorylation HPRD 17924679
Site PTM Type PTM Enzyme Score Source PMID
Y55 Phosphorylation HPRD 17924679


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K20 R20 Biomuta DOID:4159 / skin cancer [ cosmic ]
K53 * Biomuta DOID:363 / uterine cancer [ cosmic ]
N202 K202 Biomuta DOID:3571 / liver cancer [ cosmic ]
K225 N225 Biomuta DOID:363 / uterine cancer [ icgc ]
K284 T284 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]