Protein Information

Cytoscape View


UniProt AC / UniProt ID Q93063 / EXT2_HUMAN
Protein Name Exostosin-2
Gene Name Name: EXT2
Organism Homo sapiens (Human)

PRO ID PR:Q93063
DAG View
PRO Name exostosin-2 (human)
Definition An exostosin-2 that is encoded in the genome of human.
Short Label hEXT2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q93063 (EXT2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S75 Phosphorylation PhosphoSitePlus
K112 Ubiquitination PhosphoSitePlus
K113 Ubiquitination PhosphoSitePlus
K168 Ubiquitination PhosphoSitePlus
K245 Ubiquitination PhosphoSitePlus
K275 Ubiquitination PhosphoSitePlus
K285 Ubiquitination PhosphoSitePlus
N288 N-Glycosylation GlyGen 23090970, 24190977
K369 Ubiquitination PhosphoSitePlus
K478 Ubiquitination PhosphoSitePlus
K484 Ubiquitination PhosphoSitePlus
K494 Ubiquitination PhosphoSitePlus
K504 Ubiquitination PhosphoSitePlus
K510 Ubiquitination PhosphoSitePlus
K518 Ubiquitination PhosphoSitePlus
K579 Ubiquitination PhosphoSitePlus
K645 Ubiquitination PhosphoSitePlus
K653 Ubiquitination PhosphoSitePlus
K679 Ubiquitination PhosphoSitePlus
K690 Ubiquitination PhosphoSitePlus
K702 Ubiquitination PhosphoSitePlus
K708 Ubiquitination PhosphoSitePlus
K710 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K113 N113 Biomuta DOID:10283 / prostate cancer [ cosmic ]
K369 N369 Biomuta DOID:1324 / lung cancer [ cosmic ]
K504 Q504 Biomuta DOID:263 / kidney cancer [ cosmic, tcga ]
K518 N518 Biomuta DOID:3571 / liver cancer [ icgc ]
K679 T679 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]