iPTMnet Report for Q93045 (STMN2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q93045 / STMN2_HUMAN
Protein Name Stathmin-2
Gene Name Name: STMN2
Synonyms:SCG10,SCGN10;
Organism Homo sapiens (Human)

PRO ID PR:Q93045
DAG View
PRO Name stathmin-2 (human)
Definition A stathmin-2 that is encoded in the genome of human.
Short Label hSTMN2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q93045 (STMN2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y35 Phosphorylation PhosphoSitePlus
S50 Phosphorylation O96013 (PAK4) PhosphoSitePlus   RLIMS-P 23893240, 15825189
S62 Phosphorylation P45983 (MAPK8) , P53779 (MAPK10) , P27361 (MAPK3) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 11718727, 9525956, 24275569, ...16618812
S73 Phosphorylation P53779 (MAPK10) , P27361 (MAPK3) , P45983 (MAPK8) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 11718727, 9525956, 16618812
K77 Ubiquitination PhosphoSitePlus
S80 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K86 Acetylation PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
K87 Acetylation PhosphoSitePlus
K87 Ubiquitination PhosphoSitePlus
S97 Phosphorylation PhosphoSitePlus   RLIMS-P 15825189
K119 Acetylation PhosphoSitePlus
K119 Ubiquitination PhosphoSitePlus
S128 Phosphorylation PhosphoSitePlus
K129 Acetylation PhosphoSitePlus
K129 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S50 Phosphorylation P17612 (PRKACA) HPRD 9525956, 9126608
S62 Phosphorylation P27361 (MAPK3) HPRD 9525956, 9126608
S73 Phosphorylation P06493 (CDK1) , P27361 (MAPK3) HPRD 9525956, 9126608
S80 Phosphorylation HPRD 18669648, 20068231
S97 Phosphorylation P17612 (PRKACA) HPRD 9525956, 9126608


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S50 F50 Biomuta DOID:4159 / skin cancer [ cosmic ]
S62 F62 Biomuta DOID:4159 / skin cancer [ cosmic ]
S73 F73 Biomuta DOID:4159 / skin cancer [ cosmic ]
S73 Y73 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S80 F80 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K87 Q87 Biomuta [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]