Protein Information

Cytoscape View


UniProt AC / UniProt ID Q92997 / DVL3_HUMAN
Protein Name Segment polarity protein dishevelled homolog DVL-3
Gene Name Name: DVL3
Synonyms:KIAA0208;
Organism Homo sapiens (Human)

PRO ID PR:Q92997
DAG View
PRO Name segment polarity protein dishevelled homolog DVL-3 (human)
Definition A segment polarity protein dishevelled DVL-3 that is encoded in the genome of human.
Short Label hDVL3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q92997 (DVL3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Ubiquitination PRO
T15 Phosphorylation PhosphoSitePlus
R27 Methylation PhosphoSitePlus   UniProt 22612246
K34 Ubiquitination PhosphoSitePlus
S41 Phosphorylation PhosphoSitePlus
S48 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
S61 Phosphorylation PhosphoSitePlus
S116 Phosphorylation PhosphoSitePlus
S125 Phosphorylation PhosphoSitePlus   UniProt 24275569
T133 Phosphorylation PhosphoSitePlus
T135 Phosphorylation PhosphoSitePlus
S137 Phosphorylation PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus
S175 Phosphorylation PhosphoSitePlus
S192 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 22612246, 24275569
S197 Phosphorylation PhosphoSitePlus
S202 Phosphorylation PhosphoSitePlus
S203 Phosphorylation PhosphoSitePlus
S204 Phosphorylation PhosphoSitePlus
T205 Phosphorylation PhosphoSitePlus
S208 Phosphorylation PhosphoSitePlus
S209 Phosphorylation PhosphoSitePlus
S211 Phosphorylation PhosphoSitePlus
R212 Methylation PhosphoSitePlus   UniProt 22612246
S232 Phosphorylation PhosphoSitePlus
S234 Phosphorylation PhosphoSitePlus
S237 Phosphorylation PhosphoSitePlus
S244 Phosphorylation PhosphoSitePlus
Y257 Phosphorylation PhosphoSitePlus
S268 Phosphorylation PhosphoSitePlus
R271 Methylation UniProt 23150776
S280 Phosphorylation PhosphoSitePlus
K283 Ubiquitination PhosphoSitePlus
S311 Phosphorylation PhosphoSitePlus
K325 Ubiquitination PhosphoSitePlus
S340 Phosphorylation PhosphoSitePlus
R342 Methylation PhosphoSitePlus   UniProt 23150776, 22612246
T346 Phosphorylation PhosphoSitePlus   UniProt 22612246
S350 Phosphorylation PhosphoSitePlus
S421 Phosphorylation PhosphoSitePlus
K466 Ubiquitination PhosphoSitePlus
K473 Ubiquitination PhosphoSitePlus
S512 Phosphorylation PhosphoSitePlus
S516 Phosphorylation PhosphoSitePlus
S564 Phosphorylation PhosphoSitePlus
S566 Phosphorylation PhosphoSitePlus
S567 Phosphorylation PhosphoSitePlus
S570 Phosphorylation PhosphoSitePlus
S573 Phosphorylation PhosphoSitePlus
S575 Phosphorylation PhosphoSitePlus
S576 Phosphorylation PhosphoSitePlus
S578 Phosphorylation PhosphoSitePlus
S596 Phosphorylation PhosphoSitePlus
S598 Phosphorylation PhosphoSitePlus
S601 Phosphorylation PhosphoSitePlus
S603 Phosphorylation PhosphoSitePlus
S605 Phosphorylation PhosphoSitePlus
T608 Phosphorylation PhosphoSitePlus
T609 Phosphorylation PhosphoSitePlus
S611 Phosphorylation PhosphoSitePlus
S612 Phosphorylation PhosphoSitePlus
S622 Phosphorylation PhosphoSitePlus
S625 Phosphorylation PhosphoSitePlus
S633 Phosphorylation PhosphoSitePlus
S636 Phosphorylation PhosphoSitePlus
S639 Phosphorylation PhosphoSitePlus
S642 Phosphorylation PhosphoSitePlus
S643 Phosphorylation PhosphoSitePlus
S689 Phosphorylation PhosphoSitePlus
S697 Phosphorylation PhosphoSitePlus   UniProt 23186163
R698 Methylation PhosphoSitePlus   UniProt 22612246
S700 Phosphorylation PhosphoSitePlus   UniProt 22612246
Site PTM Type PTM Enzyme Score Source PMID
S192 Phosphorylation HPRD 18669648


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000047227 (hDVL3/UbiqLys+) ub PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S61 L61 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
T135 R135 Biomuta DOID:263 / kidney cancer [ cosmic ]
S209 C209 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
R212 C212 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K283 N283 Biomuta DOID:1324 / lung cancer [ cosmic ]
S564 G564 Biomuta DOID:11054 / urinary bladder cancer [ icgc ]
S576 G576 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]