iPTMnet Report for Q92979 (EMG1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q92979 / NEP1_HUMAN
Protein Name Ribosomal RNA small subunit methyltransferase NEP1
Gene Name Name: EMG1
Synonyms:C2F;
Organism Homo sapiens (Human)

PRO ID PR:Q92979
DAG View
PRO Name ribosomal RNA small subunit methyltransferase NEP1 (human)
Definition A ribosomal RNA small subunit methyltransferase NEP1 that is encoded in the genome of human.
Short Label hEMG1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q92979 (EMG1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
S5 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 19007248, 20068231, ...19691289
K9 Acetylation PhosphoSitePlus
K9 Ubiquitination PhosphoSitePlus
S14 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 19007248, 20068231
K28 Ubiquitination PhosphoSitePlus
K37 Ubiquitination PhosphoSitePlus
S51 Phosphorylation HPRD   PhosphoSitePlus 20068231
T54 Phosphorylation HPRD   PhosphoSitePlus 20068231
K59 Acetylation PhosphoSitePlus
K59 Ubiquitination PhosphoSitePlus
Y61 Phosphorylation PhosphoSitePlus
C66 Methylation IEDB 31844290
C66 S-Nitrosylation dbSNO 26338901
K68 Acetylation PhosphoSitePlus
K68 Ubiquitination PhosphoSitePlus
K70 Ubiquitination PhosphoSitePlus
K75 Ubiquitination PhosphoSitePlus
S91 Phosphorylation PhosphoSitePlus
K154 Ubiquitination PhosphoSitePlus
K160 Ubiquitination PhosphoSitePlus
Y222 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S5 N5 Biomuta DOID:4159 / skin cancer [ cosmic ]
S5 C5 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K37 E37 Biomuta DOID:1324 / lung cancer [ cosmic ]
K160 R160 Biomuta DOID:9256 / colorectal cancer [ cosmic ]