iPTMnet Report for Q92932 (PTPRN2)
Protein Information
| UniProt AC / UniProt ID | Q92932 / PTPR2_HUMAN |
| Protein Name | Receptor-type tyrosine-protein phosphatase N2 precursor |
| Gene Name | Name: PTPRN2 Synonyms:KIAA0387; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q92932 |
| PRO Name | receptor-type tyrosine-protein phosphatase N2 (human) |
| Definition | A receptor-type tyrosine-protein phosphatase N2 that is encoded in the genome of human. |
| Short Label | hPTPRN2 |
| Category | organism-gene |
DAG ViewQ92932 (PTPRN2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S25 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S26 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S124 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S129 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y139 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T199 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T220 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
| T220 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S230 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
| S230 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S247 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y249 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S360 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T398 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
| S433 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S434 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S436 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S437 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T619 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S622 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S643 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y666 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S695 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S704 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S776 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K970 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
| T977 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S360 | Phosphorylation | score0 | HPRD | 18702456 | ||
| T441 | Phosphorylation | score0 | HPRD | 18702456 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S124 | R124 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| T199 | M199 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| S247 | C247 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S343 | Y343 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S360 | Y360 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S433 | C433 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S434 | F434 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S436 | F436 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic ] | |
| S622 | Y622 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| Y666 | F666 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S704 | I704 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S776 | F776 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S776 | P776 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc, cosmic, icgc ] |
