iPTMnet Report for Q92925 (SMARCD2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q92925 / SMRD2_HUMAN
Protein Name SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2
Gene Name Name: SMARCD2
Synonyms:BAF60B;ORFNames:PRO2451;
Organism Homo sapiens (Human)

PRO ID PR:Q92925
DAG View
PRO Name SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 (human)
Definition A SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 that is encoded in the genome of human.
Short Label hSMARCD2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q92925 (SMARCD2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R4 Methylation PhosphoSitePlus
S15 Phosphorylation PhosphoSitePlus
R73 Methylation PhosphoSitePlus
R81 Methylation PhosphoSitePlus   UniProt 24129315
R104 Methylation PhosphoSitePlus   UniProt 24129315
R116 Methylation PhosphoSitePlus
R118 Methylation PhosphoSitePlus
K143 Ubiquitination PhosphoSitePlus
Y159 Phosphorylation PhosphoSitePlus
K168 Sumoylation PhosphoSitePlus
K168 Ubiquitination PhosphoSitePlus
K185 Ubiquitination PhosphoSitePlus
Y197 Phosphorylation PhosphoSitePlus
S199 Phosphorylation PhosphoSitePlus
T201 Phosphorylation PhosphoSitePlus
S203 Phosphorylation PhosphoSitePlus   UniProt 23186163
S205 Phosphorylation PhosphoSitePlus
K206 Ubiquitination PhosphoSitePlus
S211 Phosphorylation PhosphoSitePlus
T214 Phosphorylation PhosphoSitePlus
T217 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 16964243, ...18669648, 24275569, 20068231
T221 Phosphorylation PhosphoSitePlus
K226 Ubiquitination PhosphoSitePlus
K237 Ubiquitination PhosphoSitePlus
K244 Ubiquitination PhosphoSitePlus
K248 Ubiquitination PhosphoSitePlus
K262 Ubiquitination PhosphoSitePlus
K289 Ubiquitination PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
T299 O-Glycosylation GlyGen 33214551, 34019948, 29351928
K312 Ubiquitination PhosphoSitePlus
T325 Phosphorylation PhosphoSitePlus
T327 Phosphorylation PhosphoSitePlus
Y338 Phosphorylation PhosphoSitePlus
Y352 Phosphorylation PhosphoSitePlus
K376 Ubiquitination PhosphoSitePlus
K401 Ubiquitination PhosphoSitePlus
K451 Ubiquitination PhosphoSitePlus
K480 Ubiquitination PhosphoSitePlus
T483 Phosphorylation PhosphoSitePlus
K514 Ubiquitination PhosphoSitePlus
R529 Methylation PhosphoSitePlus
T531 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S203 Phosphorylation HPRD 20068231
T217 Phosphorylation HPRD 19413330, 16964243, 19664994, ...19664995, 19691289, 18669648, 20068231
Y338 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R73 Q73 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R81 Q81 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R104 Q104 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic, icgc ]
R104 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R104 L104 Biomuta DOID:1319 / brain cancer [ cosmic ]
R116 Q116 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
R116 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R118 H118 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R118 C118 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y197 * Biomuta DOID:3571 / liver cancer [ cosmic ]
S199 F199 Biomuta DOID:4159 / skin cancer [ cosmic ]
K401 * Biomuta DOID:3571 / liver cancer [ cosmic ]