iPTMnet Report for Q92911 (SLC5A5)
Protein Information
UniProt AC / UniProt ID | Q92911 / SC5A5_HUMAN |
Protein Name | Sodium/iodide cotransporter |
Gene Name | Name: SLC5A5 Synonyms:NIS; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q92911 |
PRO Name | sodium/iodide cotransporter (human) |
Definition | A sodium/iodide cotransporter that is encoded in the genome of human. |
Short Label | hSLC5A5 |
Category | organism-gene |
Q92911 (SLC5A5) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S43 | Phosphorylation | score1 | PhosphoSitePlus | |||
S66 | Phosphorylation | score1 | PhosphoSitePlus | |||
S126 | Phosphorylation | score1 | PhosphoSitePlus | |||
S227 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 17913707 | ||
S377 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S43 | R43 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S43 | T43 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
S227 | Y227 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |