iPTMnet Report for Q92890 (UFD1)
Protein Information
UniProt AC / UniProt ID | Q92890 / UFD1_HUMAN |
Protein Name | Ubiquitin recognition factor in ER-associated degradation protein 1 |
Gene Name | Name: UFD1 Synonyms:UFD1L; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q92890 |
PRO Name | ubiquitin recognition factor in ER-associated degradation protein 1 (human) |
Definition | A ubiquitin recognition factor in ER-associated degradation protein 1 that is encoded in the genome of human. |
Short Label | hUFD1 |
Category | organism-gene |
Q92890 (UFD1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 19413330 | ||
S3 | Phosphorylation | score1 | PhosphoSitePlus | |||
S27 | Phosphorylation | score1 | PhosphoSitePlus | |||
S29 | Phosphorylation | score1 | PhosphoSitePlus | |||
K45 | Ubiquitination | score1 | PhosphoSitePlus | |||
K68 | Ubiquitination | score1 | PhosphoSitePlus | |||
K72 | Ubiquitination | score1 | PhosphoSitePlus | |||
T78 | Phosphorylation | score1 | PhosphoSitePlus | |||
C80 | Methylation | score1 | IEDB | 31844290 | ||
C92 | Methylation | score1 | IEDB | 31844290 | ||
K124 | Ubiquitination | score1 | PhosphoSitePlus | |||
S129 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
T136 | Phosphorylation | score1 | PhosphoSitePlus | |||
K139 | Ubiquitination | score1 | PhosphoSitePlus | |||
K165 | Ubiquitination | score1 | PhosphoSitePlus | |||
R170 | Methylation | score1 | PhosphoSitePlus | |||
K175 | Ubiquitination | score1 | PhosphoSitePlus | |||
K178 | Ubiquitination | score1 | PhosphoSitePlus | |||
K198 | Ubiquitination | score1 | PhosphoSitePlus | |||
S209 | Phosphorylation | score1 | PhosphoSitePlus | |||
T210 | Phosphorylation | score1 | PhosphoSitePlus | |||
S217 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y219 | Phosphorylation | score1 | PhosphoSitePlus | |||
S229 | Phosphorylation | score1 | PhosphoSitePlus | |||
S231 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 20068231 | ||
K238 | Acetylation | score1 | PhosphoSitePlus | |||
K240 | Ubiquitination | score1 | PhosphoSitePlus | |||
S245 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 20068231 | ||
S247 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 20068231 | ||
K250 | Acetylation | score1 | PhosphoSitePlus | |||
K250 | Ubiquitination | score1 | PhosphoSitePlus | |||
K255 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y261 | Phosphorylation | score1 | PhosphoSitePlus | |||
K264 | Ubiquitination | score1 | PhosphoSitePlus | |||
K267 | Ubiquitination | score1 | PhosphoSitePlus | |||
K279 | Ubiquitination | score1 | PhosphoSitePlus | |||
K280 | Ubiquitination | score1 | PhosphoSitePlus | |||
S294 | Phosphorylation | score1 | PhosphoSitePlus | |||
S299 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692, 23186163, 18669648, ... | ||
K302 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T210 | Phosphorylation | score0 | HPRD | 20068231 | ||
S231 | Phosphorylation | score0 | HPRD | 20068231 | ||
S245 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 20068231 | ||
S247 | Phosphorylation | score0 | HPRD | 17322306, 19651622, 18669648, ... | ||
S299 | Phosphorylation | score0 | HPRD | 18491316, 17287340, 18767875, ... |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S3 | Y3 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
S27 | F27 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
S29 | F29 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
C80 | Y80 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:4159 / skin cancer [ cosmic ] | |
K124 | R124 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
K124 | T124 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
T136 | A136 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
K198 | N198 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
S209 | L209 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] | |
S231 | F231 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K250 | N250 | Biomuta | DOID:3953 / adrenal gland cancer [ cosmic ] | |
K255 | E255 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic ] | |
Y261 | C261 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
K280 | E280 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |