iPTMnet Report for Q92870 (APBB2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q92870 / APBB2_HUMAN
Protein Name Amyloid beta precursor protein binding family B member 2
Gene Name Name: APBB2
Synonyms:FE65L;
Organism Homo sapiens (Human)

PRO ID PR:Q92870
DAG View
PRO Name amyloid beta precursor protein binding family B member 2 (human)
Definition An amyloid beta precursor protein binding family B member 2 that is encoded in the genome of human.
Short Label hAPBB2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q92870 (APBB2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S31 Phosphorylation PhosphoSitePlus
T34 Phosphorylation PhosphoSitePlus
T38 Phosphorylation PhosphoSitePlus
K54 Ubiquitination PhosphoSitePlus
T62 Phosphorylation PhosphoSitePlus
S123 Phosphorylation PhosphoSitePlus   UniProt 21406692, 24275569
K159 Ubiquitination PhosphoSitePlus
S160 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y164 Phosphorylation PhosphoSitePlus
S216 Phosphorylation PhosphoSitePlus
S217 Phosphorylation PhosphoSitePlus
S229 Phosphorylation PhosphoSitePlus
K238 Acetylation PhosphoSitePlus
K242 Ubiquitination PhosphoSitePlus
S330 Phosphorylation PhosphoSitePlus
K332 Ubiquitination PhosphoSitePlus
S334 Phosphorylation PhosphoSitePlus   UniProt 24275569
S336 Phosphorylation PhosphoSitePlus
S337 Phosphorylation PhosphoSitePlus
T339 Phosphorylation PhosphoSitePlus
S341 Phosphorylation PhosphoSitePlus
T343 Phosphorylation PhosphoSitePlus
S364 Phosphorylation PhosphoSitePlus
S380 Phosphorylation PhosphoSitePlus
K382 Ubiquitination PhosphoSitePlus
T388 Phosphorylation PhosphoSitePlus
Y391 Phosphorylation PhosphoSitePlus
S393 Phosphorylation PhosphoSitePlus
S409 Phosphorylation PhosphoSitePlus
S412 Phosphorylation PhosphoSitePlus
K438 Ubiquitination PhosphoSitePlus
K454 Ubiquitination PhosphoSitePlus
K556 Ubiquitination PhosphoSitePlus
S658 Phosphorylation PhosphoSitePlus
S716 Phosphorylation PhosphoSitePlus
S743 Phosphorylation PhosphoSitePlus
T747 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S123 Phosphorylation HPRD 19651622, 18767875, 20068231
T125 Phosphorylation HPRD 19651622
S330 Phosphorylation HPRD 19664994
S334 Phosphorylation PhosphoSitePlus
S336 Phosphorylation HPRD 19413330
S341 Phosphorylation PhosphoSitePlus
T343 Phosphorylation HPRD 19413330
T559 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S216 F216 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S334 P334 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S334 L334 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T339 M339 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S341 F341 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S743 F743 Biomuta [ cosmic ] DOID:4159 / skin cancer [ cosmic ]
T747 N747 Biomuta DOID:4159 / skin cancer [ cosmic, icgc, cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic ]