Protein Information

Cytoscape View


UniProt AC / UniProt ID Q92859 / NEO1_HUMAN
Protein Name Neogenin precursor
Gene Name Name: NEO1
Synonyms:IGDCC2,NGN;
Organism Homo sapiens (Human)

PRO ID PR:Q92859
DAG View
PRO Name neogenin (human)
Definition A neogenin that is encoded in the genome of human.
Short Label hNEO1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q92859 (NEO1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T51 Phosphorylation PhosphoSitePlus
S68 Phosphorylation PhosphoSitePlus
S69 Phosphorylation PhosphoSitePlus
N73 N-Glycosylation GlyGen 23090970, 24190977
Y164 Phosphorylation PhosphoSitePlus
N210 N-Glycosylation GlyGen   UniProt 16335952, 24190977, 29391424, ...19349973
Y219 Phosphorylation PhosphoSitePlus
S225 Phosphorylation PhosphoSitePlus
N377 N-Glycosylation GlyGen 24190977
T434 O-Glycosylation GlyGen 30459171
N470 N-Glycosylation GlyGen   UniProt 23090970, 24190977, 29391424, ...19349973
N489 N-Glycosylation GlyGen   UniProt 16335952
Y602 Phosphorylation PhosphoSitePlus
T603 Phosphorylation PhosphoSitePlus
N639 N-Glycosylation GlyGen   UniProt 23090970, 24190977, 29391424, ...19349973
T846 O-Glycosylation GlyGen 30459171
K904 Acetylation PhosphoSitePlus
T955 Phosphorylation PhosphoSitePlus
S956 Phosphorylation PhosphoSitePlus
S1056 Phosphorylation PhosphoSitePlus
S1057 Phosphorylation PhosphoSitePlus
S1066 Phosphorylation PhosphoSitePlus
S1068 Phosphorylation PhosphoSitePlus
S1080 Phosphorylation PhosphoSitePlus
Y1082 Phosphorylation PhosphoSitePlus
N1146 N-Glycosylation GlyGen 29391424
K1173 Ubiquitination PhosphoSitePlus
S1178 O-Glycosylation GlyGen 30379171
S1178 Phosphorylation PhosphoSitePlus
T1188 Phosphorylation PhosphoSitePlus
S1194 Phosphorylation PhosphoSitePlus   UniProt 24275569
T1198 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1203 Phosphorylation PhosphoSitePlus
S1214 Phosphorylation PhosphoSitePlus
S1220 Phosphorylation PhosphoSitePlus
Y1279 Phosphorylation PhosphoSitePlus
T1289 Phosphorylation PhosphoSitePlus
S1292 Phosphorylation PhosphoSitePlus
S1294 Phosphorylation PhosphoSitePlus
N1298 N-Glycosylation GlyGen 29391424
S1299 Phosphorylation PhosphoSitePlus
T1300 Phosphorylation PhosphoSitePlus
S1302 Phosphorylation PhosphoSitePlus
T1382 Phosphorylation PhosphoSitePlus
S1386 Phosphorylation PhosphoSitePlus
S1401 Phosphorylation PhosphoSitePlus   UniProt 23186163
T1404 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1432 Phosphorylation PhosphoSitePlus
S1434 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1435 Phosphorylation PhosphoSitePlus
Y1436 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S956 Y956 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1194 A1194 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S1220 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S1302 F1302 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1302 Y1302 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1401 F1401 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic, icgc ]
T1404 I1404 Biomuta DOID:9256 / colorectal cancer [ cosmic ]