Protein Information

Cytoscape View

UniProt AC / UniProt ID Q92854 / SEM4D_HUMAN
Protein Name Semaphorin-4D precursor
Gene Name Name: SEMA4D
Organism Homo sapiens (Human)

PRO ID PR:Q92854
DAG View
PRO Name semaphorin-4D (human)
Definition A semaphorin-4D that is encoded in the genome of human.
Short Label hSEMA4D
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q92854 (SEMA4D) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
T5 Phosphorylation PhosphoSitePlus
N49 N-Glycosylation UniProt 20877282, 19349973
N77 N-Glycosylation UniProt 20877282, 19349973
K81 Ubiquitination PhosphoSitePlus
K104 Ubiquitination PhosphoSitePlus
N139 N-Glycosylation UniProt 20877282
K148 Ubiquitination PhosphoSitePlus
N191 N-Glycosylation UniProt 20877282
K269 Acetylation PhosphoSitePlus
K276 Acetylation PhosphoSitePlus
N329 N-Glycosylation UniProt 20877282
N379 N-Glycosylation UniProt 19349973
T390 Phosphorylation PhosphoSitePlus
N419 N-Glycosylation UniProt 16263699, 20877282, 19349973
K505 Ubiquitination PhosphoSitePlus
S547 Phosphorylation PhosphoSitePlus
S551 Phosphorylation PhosphoSitePlus
Y561 Phosphorylation PhosphoSitePlus
K575 Ubiquitination PhosphoSitePlus
T657 O-Glycosylation PhosphoSitePlus
T663 O-Glycosylation PhosphoSitePlus
S666 O-Glycosylation PhosphoSitePlus
T670 O-Glycosylation PhosphoSitePlus
T716 O-Glycosylation PhosphoSitePlus
S722 O-Glycosylation PhosphoSitePlus
Y727 Phosphorylation PhosphoSitePlus
S769 Phosphorylation PhosphoSitePlus
S788 Phosphorylation PhosphoSitePlus
K790 Ubiquitination PhosphoSitePlus
S798 Phosphorylation PhosphoSitePlus
K808 Ubiquitination PhosphoSitePlus
Y815 Phosphorylation PhosphoSitePlus
T817 Phosphorylation PhosphoSitePlus
K825 Ubiquitination PhosphoSitePlus
S833 Phosphorylation PhosphoSitePlus   UniProt 23186163
S840 Phosphorylation PhosphoSitePlus
S857 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S195 Phosphorylation HPRD 17081983

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N139 S139 Biomuta DOID:363 / uterine cancer [ cosmic ]
T390 M390 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
T390 K390 Biomuta DOID:3571 / liver cancer [ icgc ]
Y561 * Biomuta DOID:3571 / liver cancer [ icgc ]
T657 S657 Biomuta DOID:3571 / liver cancer [ tcga ]
S722 L722 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S788 R788 Biomuta DOID:3571 / liver cancer [ icgc ]
S840 F840 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S857 L857 Biomuta DOID:9256 / colorectal cancer [ icgc ]