iPTMnet Report for Q92843 (BCL2L2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q92843 / B2CL2_HUMAN
Protein Name Bcl-2-like protein 2
Gene Name Name: BCL2L2
Synonyms:BCLW,KIAA0271;
Organism Homo sapiens (Human)

PRO ID PR:Q92843
DAG View
PRO Name bcl-2-like protein 2 (human)
Definition A protein that is a translation product of any of the following genes in human: BCL2L2, or a readthrough of the BCL2L2-PABPN1 genes.
Short Label h[BCL2L2/BCL2L2-PABPN1]
Category union

Interactive Sequence View

Select/align proteoforms across species


Q92843 (BCL2L2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330
T172 Phosphorylation PhosphoSitePlus
A177 Phosphorylation UniProt 18669648, 23186163, 19690332, ...20068231
S192 Phosphorylation PhosphoSitePlus
K193 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K162 Ubiquitination PhosphoSitePlus
K164 Ubiquitination PhosphoSitePlus
S177 Phosphorylation PhosphoSitePlus
T211 Phosphorylation PhosphoSitePlus
S224 Phosphorylation PhosphoSitePlus
K234 Acetylation PhosphoSitePlus
K234 Ubiquitination PhosphoSitePlus
Y244 Phosphorylation PhosphoSitePlus
K250 Ubiquitination PhosphoSitePlus
R254 Methylation PhosphoSitePlus
R265 Methylation PhosphoSitePlus
R267 Methylation PhosphoSitePlus
R286 Methylation PhosphoSitePlus
R290 Methylation PhosphoSitePlus
R294 Methylation PhosphoSitePlus
R304 Methylation PhosphoSitePlus
R314 Methylation PhosphoSitePlus
S331 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K164 N164 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S224 L224 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
R286 Q286 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ]
R294 C294 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S331 F331 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]