Protein Information

Cytoscape View

UniProt AC / UniProt ID Q92837 / FRAT1_HUMAN
Protein Name Proto-oncogene FRAT1
Gene Name Name: FRAT1
Organism Homo sapiens (Human)

PRO ID PR:Q92837
DAG View
PRO Name proto-oncogene FRAT1 (human)
Definition A proto-oncogene FRAT1 that is encoded in the genome of human.
Short Label hFRAT1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q92837 (FRAT1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S88 Phosphorylation PhosphoSitePlus   UniProt 19369195
S138 Phosphorylation PhosphoSitePlus
S188 Phosphorylation P17612 (PRKACA) , P49841 (GSK3B) , P17252 (PRKCA) neXtProt   PhosphoSitePlus   Signor 16982607
K214 Ubiquitination PhosphoSitePlus
S249 Phosphorylation PhosphoSitePlus
S279 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S188 F188 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S279 R279 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc, tcga ]