iPTMnet Report for Q92834 (RPGR)
Protein Information
UniProt AC / UniProt ID | Q92834 / RPGR_HUMAN |
Protein Name | X-linked retinitis pigmentosa GTPase regulator precursor |
Gene Name | Name: RPGR Synonyms:RP3,XLRP3; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q92834 |
PRO Name | X-linked retinitis pigmentosa GTPase regulator (human) |
Definition | An X-linked retinitis pigmentosa GTPase regulator that is encoded in the genome of human. |
Short Label | hRPGR |
Category | organism-gene |
Q92834 (RPGR) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K143 | Ubiquitination | score1 | PhosphoSitePlus | |||
T335 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y393 | Phosphorylation | score1 | PhosphoSitePlus | |||
S418 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S514 | Phosphorylation | score1 | PhosphoSitePlus | |||
S518 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S544 | Phosphorylation | score1 | PhosphoSitePlus | |||
S866 | Phosphorylation | score1 | PhosphoSitePlus | |||
T870 | Phosphorylation | score1 | PhosphoSitePlus | |||
S876 | Phosphorylation | score1 | PhosphoSitePlus | |||
S883 | Phosphorylation | score1 | PhosphoSitePlus | |||
T891 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y916 | Phosphorylation | score1 | PhosphoSitePlus | |||
S961 | Phosphorylation | score2 | IEDB PhosphoSitePlus | 33936100 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S544 | Phosphorylation | score0 | HPRD | 19413330 | ||
T686 | Phosphorylation | score0 | HPRD | 19664994 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S544 | Phosphorylation | score0 | HPRD | 19413330 | ||
K1101 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1106 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S418 | Y418 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S418 | F418 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S876 | R876 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |