iPTMnet Report for Q92831 (KAT2B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q92831 / KAT2B_HUMAN
Protein Name Histone acetyltransferase KAT2B
Gene Name Name: KAT2B
Synonyms:PCAF;
Organism Homo sapiens (Human)

PRO ID PR:Q92831
DAG View
PRO Name histone acetyltransferase KAT2B (human)
Definition A histone acetyltransferase KAT2B that is encoded in the genome of human.
Short Label hKAT2B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q92831 (KAT2B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S49 Phosphorylation PhosphoSitePlus
S72 Phosphorylation PhosphoSitePlus
K78 Acetylation PhosphoSitePlus
K78 Methylation PhosphoSitePlus
K79 Acetylation PhosphoSitePlus
K89 Methylation PhosphoSitePlus
S117 Phosphorylation PhosphoSitePlus
T119 Phosphorylation PhosphoSitePlus
S264 Phosphorylation PhosphoSitePlus   RLIMS-P 32966758
S270 Phosphorylation PhosphoSitePlus
S276 Phosphorylation PhosphoSitePlus
Y301 Phosphorylation PhosphoSitePlus
T310 Phosphorylation PhosphoSitePlus
S314 Phosphorylation PhosphoSitePlus
T317 Phosphorylation PhosphoSitePlus
K416 Acetylation PhosphoSitePlus
K428 Acetylation PhosphoSitePlus
K430 Acetylation PhosphoSitePlus
K441 Acetylation PhosphoSitePlus
K442 Acetylation PhosphoSitePlus
Y533 Phosphorylation PhosphoSitePlus
T535 Phosphorylation PhosphoSitePlus
K550 Ubiquitination PhosphoSitePlus
K638 Methylation PhosphoSitePlus
K638 Ubiquitination PhosphoSitePlus
K671 Methylation PhosphoSitePlus
K672 Methylation PhosphoSitePlus
K683 Ubiquitination PhosphoSitePlus
K692 Methylation PhosphoSitePlus
K720 Acetylation PhosphoSitePlus
Y729 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18083107
T731 Phosphorylation PhosphoSitePlus
K733 Acetylation PhosphoSitePlus
Y802 Phosphorylation PhosphoSitePlus
S807 Phosphorylation PhosphoSitePlus
Y809 Phosphorylation PhosphoSitePlus
Y810 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S49 L49 Biomuta DOID:1324 / lung cancer [ cosmic ]
K89 N89 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S117 P117 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S264 Y264 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y301 H301 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S314 * Biomuta DOID:263 / kidney cancer [ cosmic ]
S314 W314 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
K428 N428 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K638 N638 Biomuta DOID:10283 / prostate cancer [ cosmic ]
K683 E683 Biomuta DOID:1324 / lung cancer [ cosmic ]
K692 R692 Biomuta DOID:4159 / skin cancer [ cosmic ]
T731 M731 Biomuta DOID:9256 / colorectal cancer [ cosmic ]