iPTMnet Report for Q92819 (HAS2)
Protein Information
| UniProt AC / UniProt ID | Q92819 / HYAS2_HUMAN |
| Protein Name | Hyaluronan synthase 2 |
| Gene Name | Name: HAS2 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q92819 |
| PRO Name | hyaluronan synthase 2 (human) |
| Definition | A hyaluronan synthase 2 that is encoded in the genome of human. |
| Short Label | hHAS2 |
| Category | organism-gene |
DAG ViewQ92819 (HAS2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T77 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K80 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T110 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P UniProt | 21228273, 24134926 | ||
| T110 | Phosphorylation | P54646 (PRKAA2) | score2 | PhosphoSitePlus | 21228273 | |
| S180 | O-Glycosylation | score3 | GlyGen | 30379171, 22887999 | ||
| K190 | Ubiquitination | score3 | PhosphoSitePlus UniProt | 20507985 | ||
| T196 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S221 | O-Glycosylation | score4 | GlyGen UniProt | 30379171, 22887999 | ||
| S221 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T328 | Phosphorylation | score3 | PhosphoSitePlus UniProt | 32993960 | ||
| T412 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y546 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T110 | A110 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S180 | I180 | Biomuta | DOID:1793 / pancreatic cancer [ icgc ] | |
| S221 | L221 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] |
