iPTMnet Report for Q92796 (DLG3)
Protein Information
| UniProt AC / UniProt ID | Q92796 / DLG3_HUMAN |
| Protein Name | Disks large homolog 3 |
| Gene Name | Name: DLG3 Synonyms:KIAA1232; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q92796 |
| PRO Name | disks large homolog 3 (human) |
| Definition | A disks large homolog 3 that is encoded in the genome of human. |
| Short Label | hDLG3 |
| Category | organism-gene |
Q92796 (DLG3) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| M1 | Acetylation | score1 | UniProt | 22814378 | ||
| H2 | Acetylation | score1 | UniProt | 22814378 | ||
| T78 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T112 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y117 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S123 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T163 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K268 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y306 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S458 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S487 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S488 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S490 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S491 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S495 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S503 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y505 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T515 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T550 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S589 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y626 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K637 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T660 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y673 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18083107 | ||
| S678 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T759 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y760 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K765 | Acetylation | score1 | PhosphoSitePlus | |||
| Y808 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18083107 | ||
| S813 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T112 | Phosphorylation | score0 | HPRD | 20058876 | ||
| Y117 | Phosphorylation | score0 | HPRD | 20058876 | ||
| S123 | Phosphorylation | score0 | HPRD | 20058876 | ||
| Y673 | Phosphorylation | score0 | HPRD | 18083107, 19901323, 17389395 | ||
| Y808 | Phosphorylation | score0 | HPRD | 18083107 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K6 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S8 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S252 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S255 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K261 | Methylation | score1 | PhosphoSitePlus | |||
| K261 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S263 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S267 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S275 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K276 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S283 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S284 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T294 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S295 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y368 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18083107, 17389395, 19901323 | ||
| T454 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y503 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18083107 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S252 | F252 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S255 | L255 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S267 | Y267 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S275 | N275 | Biomuta | DOID:4362 / cervical cancer [ icgc ] | |
| S284 | I284 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| T294 | P294 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| Y368 | H368 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S490 | N490 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S491 | C491 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S503 | F503 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| T550 | S550 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc ] | |
| S589 | F589 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| Y673 | H673 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
DAG View