iPTMnet Report for Q92794 (KAT6A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q92794 / KAT6A_HUMAN
Protein Name Histone acetyltransferase KAT6A
Gene Name Name: KAT6A
Synonyms:MOZ,MYST3,RUNXBP2,ZNF220;
Organism Homo sapiens (Human)

PRO ID PR:Q92794
DAG View
PRO Name histone acetyltransferase KAT6A (human)
Definition A histone acetyltransferase KAT6A that is encoded in the genome of human.
Short Label hKAT6A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q92794 (KAT6A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S28 Phosphorylation HPRD 20068231
K90 Acetylation PhosphoSitePlus
S116 Phosphorylation PhosphoSitePlus
T117 Phosphorylation PhosphoSitePlus
S132 Phosphorylation PhosphoSitePlus
S138 Phosphorylation PhosphoSitePlus
S141 Phosphorylation PhosphoSitePlus
S245 Phosphorylation PhosphoSitePlus
T332 Phosphorylation PhosphoSitePlus
T347 Phosphorylation PhosphoSitePlus
K350 Acetylation PhosphoSitePlus   UniProt 19608861
K355 Acetylation PhosphoSitePlus   UniProt 19608861
T369 Phosphorylation P31749 (AKT1) PRO   PhosphoSitePlus   RLIMS-P   UniProt 23431171
S379 Phosphorylation PhosphoSitePlus
Y383 Phosphorylation PhosphoSitePlus
K415 Acetylation PhosphoSitePlus
K415 Ubiquitination PhosphoSitePlus
T418 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S420 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
Y433 Phosphorylation PhosphoSitePlus
Y437 Phosphorylation PhosphoSitePlus
S447 Phosphorylation HPRD   PhosphoSitePlus 20068231
S448 Phosphorylation PhosphoSitePlus
T449 Phosphorylation HPRD   PhosphoSitePlus 19413330
S450 Phosphorylation PhosphoSitePlus
K463 Ubiquitination PhosphoSitePlus
S473 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17525332, 23186163, 20068231
K480 Ubiquitination PhosphoSitePlus
K495 Ubiquitination PhosphoSitePlus
K604 Acetylation PhosphoSitePlus
S678 Phosphorylation PhosphoSitePlus
S787 Phosphorylation PhosphoSitePlus
S812 Phosphorylation PhosphoSitePlus   UniProt 23186163
K815 Acetylation PhosphoSitePlus
S826 Phosphorylation PhosphoSitePlus
S828 Phosphorylation PhosphoSitePlus
S842 Phosphorylation HPRD 20068231
C902 S-Nitrosylation dbSNO 26338901
T909 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17525332
S941 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 20068231, 18220336
S954 Phosphorylation PhosphoSitePlus   UniProt 23186163
S974 Phosphorylation PhosphoSitePlus   UniProt 23186163
S996 Phosphorylation PhosphoSitePlus
S999 Phosphorylation PhosphoSitePlus
S1001 Phosphorylation PhosphoSitePlus
K1007 Acetylation PhosphoSitePlus   UniProt 19608861
K1014 Acetylation PhosphoSitePlus
T1042 Phosphorylation PhosphoSitePlus
S1052 Phosphorylation PhosphoSitePlus
S1054 Phosphorylation PhosphoSitePlus
S1089 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S1090 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1104 Phosphorylation HPRD   PhosphoSitePlus 19651622
S1113 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 18452278, ...18669648, 19690332, 20068231
T1119 Phosphorylation PhosphoSitePlus
S1126 Phosphorylation PhosphoSitePlus
S1136 Phosphorylation PhosphoSitePlus
T1142 Phosphorylation PhosphoSitePlus
S1143 Phosphorylation PhosphoSitePlus
T1144 Phosphorylation PhosphoSitePlus
K1147 Methylation PhosphoSitePlus
K1148 Methylation PhosphoSitePlus
K1174 Methylation PhosphoSitePlus
K1330 Methylation PhosphoSitePlus
C1630 Methylation IEDB 31844290
Y1732 Phosphorylation PhosphoSitePlus
S1745 O-Glycosylation GlyGen 30620550
S1772 O-Glycosylation GlyGen 34019948, 29351928
S1774 O-Glycosylation GlyGen 34019948, 29351928
T1778 O-Glycosylation GlyGen 34019948, 29351928
S1779 O-Glycosylation GlyGen 34019948, 29351928
S1861 Phosphorylation PhosphoSitePlus
R1877 Methylation PhosphoSitePlus
R1889 Methylation PhosphoSitePlus
R2003 Methylation PhosphoSitePlus
R2004 Methylation PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048091 (hKAT6A/Phos:1) pT369 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S28 L28 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S245 F245 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T332 A332 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T369 I369 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T369 N369 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S379 P379 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
Y383 F383 Biomuta DOID:1324 / lung cancer [ cosmic ]
T418 I418 Biomuta DOID:363 / uterine cancer [ icgc ]
Y433 C433 Biomuta DOID:4159 / skin cancer [ cosmic ]
S447 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S826 C826 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S842 T842 Biomuta DOID:1612 / breast cancer [ cosmic ]
S974 N974 Biomuta DOID:1612 / breast cancer [ cosmic ]
S999 * Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S1001 L1001 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1113 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1113 L1113 Biomuta DOID:1324 / lung cancer [ cosmic ]
T1144 I1144 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K1148 M1148 Biomuta DOID:3571 / liver cancer [ cosmic ]
K1174 N1174 Biomuta DOID:263 / kidney cancer [ cosmic ]
K1330 R1330 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1772 N1772 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T1778 N1778 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S1779 F1779 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R1877 H1877 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
R1877 C1877 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
R1889 H1889 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]