Protein Information

Cytoscape View


UniProt AC / UniProt ID Q92783 / STAM1_HUMAN
Protein Name Signal transducing adapter molecule 1
Gene Name Name: STAM
Synonyms:STAM1;
Organism Homo sapiens (Human)

PRO ID PR:Q92783
DAG View
PRO Name signal transducing adapter molecule 1 (human)
Definition A signal transducing adapter molecule 1 that is encoded in the genome of human.
Short Label hSTAM
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q92783 (STAM) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S91 Phosphorylation PhosphoSitePlus
K99 Ubiquitination PhosphoSitePlus
K103 Ubiquitination PhosphoSitePlus
K133 Ubiquitination PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
K154 Ubiquitination PhosphoSitePlus
S156 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16964243, 20068231
K162 Ubiquitination PhosphoSitePlus
K170 Ubiquitination PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus
K178 Ubiquitination PhosphoSitePlus
S183 Phosphorylation PhosphoSitePlus
K185 Ubiquitination PhosphoSitePlus
T196 Phosphorylation PhosphoSitePlus
Y198 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 10993906, 17081983, 11687594
S200 Phosphorylation PhosphoSitePlus
T201 Phosphorylation PhosphoSitePlus
S202 Phosphorylation PhosphoSitePlus
S203 Phosphorylation PhosphoSitePlus
T206 Phosphorylation PhosphoSitePlus
K276 Ubiquitination PhosphoSitePlus
K353 Ubiquitination PhosphoSitePlus
S355 Phosphorylation PhosphoSitePlus
Y371 Phosphorylation PhosphoSitePlus
T372 Phosphorylation PhosphoSitePlus
Y381 Phosphorylation PhosphoSitePlus   UniProt 20494825
S382 Phosphorylation PhosphoSitePlus
Y384 Phosphorylation PhosphoSitePlus   UniProt 20494825
Site PTM Type PTM Enzyme Score Source PMID
S147 Phosphorylation HPRD 20068231
S156 Phosphorylation HPRD 20068231
Y198 Phosphorylation HPRD 10993906, 11687594
Y381 Phosphorylation HPRD 19901323, 15951569


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S147 Y147 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S156 N156 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K162 Q162 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K162 N162 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K170 N170 Biomuta DOID:363 / uterine cancer [ icgc ]
K178 N178 Biomuta DOID:1324 / lung cancer [ cosmic ]
S183 P183 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S202 F202 Biomuta DOID:4159 / skin cancer [ cosmic ]
S203 I203 Biomuta DOID:3571 / liver cancer [ cosmic ]