iPTMnet Report for Q92754 (TFAP2C)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q92754 / AP2C_HUMAN
Protein Name Transcription factor AP-2 gamma
Gene Name Name: TFAP2C
Organism Homo sapiens (Human)

PRO ID PR:Q92754
DAG View
PRO Name transcription factor AP-2 gamma (human)
Definition A transcription factor AP-2 gamma that is encoded in the genome of human.
Short Label hTFAP2C
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q92754 (TFAP2C) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K10 Sumoylation PRO   PhosphoSitePlus
K202 Ubiquitination PhosphoSitePlus
S236 Phosphorylation PhosphoSitePlus
S238 Phosphorylation PhosphoSitePlus
K239 Ubiquitination PhosphoSitePlus
K241 Ubiquitination PhosphoSitePlus
S252 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K281 Ubiquitination PhosphoSitePlus
K284 Ubiquitination PhosphoSitePlus
S434 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 21406692
S438 Phosphorylation PhosphoSitePlus
K444 Ubiquitination PhosphoSitePlus
K447 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S434 Phosphorylation HPRD 19413330, 18669648, 19664995


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000049424 (hTFAP2C/Sumo:1) suK10 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S236 F236 Biomuta [ cosmic ]
S252 P252 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]