iPTMnet Report for Q92733 (PRCC)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q92733 / PRCC_HUMAN
Protein Name Proline-rich protein PRCC
Gene Name Name: PRCC
Synonyms:TPRC;
Organism Homo sapiens (Human)

PRO ID PR:Q92733
DAG View
PRO Name proline-rich protein PRCC (human)
Definition A proline-rich protein PRCC that is encoded in the genome of human.
Short Label hPRCC
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q92733 (PRCC) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S8 Phosphorylation HPRD 17081983
S9 Phosphorylation HPRD 17081983
S12 Phosphorylation HPRD 17081983
S97 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20068231
S114 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20068231, 24275569
S157 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17287340, 17081983, ...18452278, 19651622, 18669648, 24275569, 18707149, 20166139, 23186163, 19415658, 20068231
S159 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17287340, 17081983, ...18452278, 19651622, 18669648, 24275569, 18707149, 23186163, 19415658, 20068231
T165 Phosphorylation HPRD   PhosphoSitePlus 19651622, 17081983, 20068231, ...19415658
T169 O-Glycosylation GlyGen 31373491
S175 O-Glycosylation GlyGen 31373491
S209 Phosphorylation PhosphoSitePlus
S212 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19651622, 20068231
S218 Phosphorylation HPRD   UniProt 19651622, 17081983
K225 Methylation PhosphoSitePlus
T226 O-Glycosylation GlyGen 34846842, 28411811, 30379171, ...34019948, 35132862, 31492838
S227 O-Glycosylation GlyGen 34846842, 28411811, 30379171, ...35132862, 34019948, 31492838, 31373491
S228 O-Glycosylation GlyGen 28411811, 30379171, 34019948, ...35132862, 31492838, 31373491
T235 O-Glycosylation GlyGen 31373491
T238 Phosphorylation HPRD   PhosphoSitePlus 20068231
T239 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18669648, 20068231
S241 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18669648, 23186163, ...20068231
S243 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19413330, 18669648
K250 Acetylation PhosphoSitePlus
T261 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18077418, 20058876, 19651622, ...18669648, 20068231
S267 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 17081983, 18077418, ...20058876, 18452278, 19651622, 18669648, 20068231
S278 Phosphorylation HPRD   PhosphoSitePlus 17081983
K414 Sumoylation PhosphoSitePlus
K428 Ubiquitination PhosphoSitePlus
K434 Acetylation PhosphoSitePlus
S440 Phosphorylation PhosphoSitePlus
K442 Acetylation PhosphoSitePlus
K443 Acetylation PhosphoSitePlus
Y459 Phosphorylation PhosphoSitePlus
K472 Ubiquitination PhosphoSitePlus
S476 O-Glycosylation GlyGen 30379171, 28411811, 35132862, ...31492838, 34019948
K479 Ubiquitination PhosphoSitePlus
K488 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S8 R8 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S159 A159 Biomuta DOID:1612 / breast cancer [ cosmic ]
T169 N169 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S209 L209 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S227 F227 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
T238 I238 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S243 C243 Biomuta DOID:184 / bone cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K250 R250 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S278 F278 Biomuta DOID:4159 / skin cancer [ cosmic ]
K428 Q428 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K442 R442 Biomuta DOID:1324 / lung cancer [ cosmic ]
K442 E442 Biomuta DOID:1612 / breast cancer [ cosmic ]
K479 * Biomuta DOID:1324 / lung cancer [ cosmic ]
K488 E488 Biomuta DOID:363 / uterine cancer [ icgc ]