iPTMnet Report for Q92731 (ESR2)
Protein Information
| UniProt AC / UniProt ID | Q92731 / ESR2_HUMAN |
| Protein Name | Estrogen receptor beta |
| Gene Name | Name: ESR2 Synonyms:ESTRB,NR3A2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q92731 |
| PRO Name | estrogen receptor beta (human) |
| Definition | An estrogen receptor beta that is encoded in the genome of human. |
| Short Label | hESR2 |
| Category | organism-gene |
DAG ViewQ92731 (ESR2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| Y36 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 24960160 | ||
| Y36 | Phosphorylation | P00519 (ABL1) | score2 | PhosphoSitePlus | 24960160 | |
| Y56 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S75 | Phosphorylation | score0 | RLIMS-P | 22370157 | ||
| S87 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus RLIMS-P UniProt | 22370157, 15862947, 19584281 | ||
| S105 | Phosphorylation | score4 | neXtProt phospho.ELM PhosphoSitePlus RLIMS-P UniProt | 10230404, 20696772, 15862947, ... | ||
| S105 | Phosphorylation | P28482 (MAPK1) | score2 | neXtProt | 10230404 | |
| S135 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C152 | Methylation | score1 | IEDB | 31844290 | ||
| S165 | Phosphorylation | score2 | phospho.ELM | 9528769 | ||
| S176 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S200 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S463 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S469 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y488 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 22930062 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y36 | H36 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| C152 | F152 | Biomuta | DOID:3571 / liver cancer [ cosmic ] |
