iPTMnet Report for Q92686 (NRGN)
Protein Information
| UniProt AC / UniProt ID | Q92686 / NEUG_HUMAN |
| Protein Name | Neurogranin |
| Gene Name | Name: NRGN |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q92686 |
| PRO Name | neurogranin (human) |
| Definition | A neurogranin that is encoded in the genome of human. |
| Short Label | hNRGN |
| Category | organism-gene |
DAG ViewQ92686 (NRGN) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| M1 | Acetylation | score1 | UniProt | 19413330 | ||
| S36 | Phosphorylation | score4 | HPRD phospho.ELM PhosphoSitePlus RLIMS-P | 10075657, 23462742, 19713936, ... | ||
| S36 | Phosphorylation | P05129 (PRKCG) | score1 | HPRD | 8080473 | |
| S36 | Phosphorylation | P05771 (PRKCB) | score1 | HPRD | 8080473 | |
| S36 | Phosphorylation | P17252 (PRKCA) | score1 | HPRD | 8080473 | |
| R38 | Methylation | score1 | PhosphoSitePlus | |||
| R68 | Methylation | score2 | PhosphoSitePlus UniProt | 24129315 |
PTM-dependent PPI
|
PTM type | Substrate | Site | Interactant | Association type | Source | PMID |
|---|---|---|---|---|---|---|---|
| Phosphorylation | Q92686 (NRGN) | S36 | P0DP23 (CALM1) | inhibited_association | eFIP | 23462742 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| R38 | Q38 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| R38 | W38 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |
