iPTMnet Report for Q92685 (ALG3)
Protein Information
UniProt AC / UniProt ID | Q92685 / ALG3_HUMAN |
Protein Name | Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase |
Gene Name | Name: ALG3 Synonyms:NOT,NOT56L; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q92685 |
PRO Name | Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase (human) |
Definition | A dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase that is encoded in the genome of human. |
Short Label | hALG3 |
Category | organism-gene |
Q92685 (ALG3) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S11 | Phosphorylation | score1 | PhosphoSitePlus | |||
S13 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
K22 | Ubiquitination | score1 | PhosphoSitePlus | |||
S166 | Phosphorylation | score1 | PhosphoSitePlus | |||
C238 | Methylation | score1 | IEDB | 31844290 | ||
K325 | Ubiquitination | score1 | PhosphoSitePlus | |||
C412 | Methylation | score1 | IEDB | 31844290 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S11 | F11 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
S166 | F166 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |