iPTMnet Report for Q92625 (ANKS1A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q92625 / ANS1A_HUMAN
Protein Name Ankyrin repeat and SAM domain-containing protein 1A
Gene Name Name: ANKS1A
Synonyms:ANKS1,KIAA0229,ODIN;
Organism Homo sapiens (Human)

PRO ID PR:Q92625
DAG View
PRO Name ankyrin repeat and SAM domain-containing protein 1A (human)
Definition An ankyrin repeat and SAM domain-containing protein 1A that is encoded in the genome of human.
Short Label hANKS1A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q92625 (ANKS1A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
G2 Acetylation UniProt 12439753
K3 Ubiquitination PhosphoSitePlus
K21 Ubiquitination PhosphoSitePlus
S29 Phosphorylation PhosphoSitePlus
K181 Ubiquitination PhosphoSitePlus
K215 Ubiquitination PhosphoSitePlus
K294 Ubiquitination PhosphoSitePlus
K309 Ubiquitination PhosphoSitePlus
T318 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163
S331 Phosphorylation PhosphoSitePlus
S333 Phosphorylation PhosphoSitePlus
S336 Phosphorylation PhosphoSitePlus
Y427 Phosphorylation PhosphoSitePlus
S445 Phosphorylation PhosphoSitePlus
Y455 Phosphorylation PhosphoSitePlus
T460 Phosphorylation PhosphoSitePlus
T463 Phosphorylation PhosphoSitePlus
K464 Ubiquitination PhosphoSitePlus
S479 Phosphorylation PhosphoSitePlus
S480 Phosphorylation PhosphoSitePlus
S481 Phosphorylation PhosphoSitePlus
S482 Phosphorylation PhosphoSitePlus
S507 Phosphorylation PhosphoSitePlus   UniProt 24275569
Y568 Phosphorylation PhosphoSitePlus
T574 O-Glycosylation GlyGen 31373491
S577 O-Glycosylation GlyGen 31373491
S579 Phosphorylation PhosphoSitePlus
T610 Phosphorylation PhosphoSitePlus
S620 Phosphorylation PhosphoSitePlus   UniProt 23186163
S622 Phosphorylation PhosphoSitePlus   UniProt 18669648
S624 Phosphorylation PhosphoSitePlus
S626 Phosphorylation PhosphoSitePlus   UniProt 23186163
S628 Phosphorylation PhosphoSitePlus   UniProt 24275569
S634 Phosphorylation PhosphoSitePlus
S645 Phosphorylation PhosphoSitePlus
S647 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15302935, 18669648, 23186163, ...21406692
S649 Phosphorylation PhosphoSitePlus
S652 Phosphorylation PhosphoSitePlus
K660 Ubiquitination PhosphoSitePlus
S661 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163, 21406692, ...20068231
S663 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18088087, ...19690332, 20068231
S666 Phosphorylation PhosphoSitePlus
S677 Phosphorylation PhosphoSitePlus   UniProt 23186163
S685 Phosphorylation PhosphoSitePlus
S692 Phosphorylation PhosphoSitePlus
T696 Phosphorylation PhosphoSitePlus
K751 Ubiquitination PhosphoSitePlus
S771 Phosphorylation PhosphoSitePlus
S828 Phosphorylation PhosphoSitePlus
Y834 Phosphorylation PhosphoSitePlus
S845 Phosphorylation PhosphoSitePlus
S854 Phosphorylation PhosphoSitePlus
S858 Phosphorylation PhosphoSitePlus
S870 Phosphorylation PhosphoSitePlus
S887 Phosphorylation PhosphoSitePlus   UniProt 23186163
S895 Phosphorylation PhosphoSitePlus
T912 Phosphorylation PhosphoSitePlus
Y922 Phosphorylation PhosphoSitePlus
S1100 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T318 Phosphorylation HPRD 18669648
Y455 Phosphorylation HPRD 17389395
T460 Phosphorylation HPRD 18452278
T463 Phosphorylation HPRD 18452278
S622 Phosphorylation HPRD 18669648
S626 Phosphorylation HPRD 17322306, 18669648
S628 Phosphorylation HPRD 18669648
S647 Phosphorylation HPRD 17322306, 19413330, 18669648, ...19664994, 19664995
S652 Phosphorylation HPRD 19664994
S661 Phosphorylation HPRD 19413330, 20230923, 20058876, ...19651622, 18669648, 20068231
S663 Phosphorylation HPRD 19413330, 18088087, 20230923, ...19664995, 18452278, 19651622, 18669648, 15345747, 19415658, 20068231
S677 Phosphorylation HPRD 19664994
Y834 Phosphorylation HPRD 19901323
Y946 Phosphorylation HPRD 18452278
S949 Phosphorylation HPRD 18452278
T958 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T318 N318 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T318 P318 Biomuta DOID:4159 / skin cancer [ cosmic ]
S331 C331 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
K464 N464 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S479 R479 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T610 I610 Biomuta DOID:1324 / lung cancer [ cosmic ]
S634 L634 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S677 Y677 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S692 L692 Biomuta DOID:4159 / skin cancer [ cosmic ]
T696 M696 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S828 F828 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y834 * Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S895 F895 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic, icgc ]
T912 N912 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
T912 I912 Biomuta [ cosmic ] DOID:363 / uterine cancer [ icgc ]
Y922 F922 Biomuta DOID:3571 / liver cancer [ cosmic ]
S949 Y949 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1100 F1100 Biomuta DOID:4159 / skin cancer [ cosmic ]