iPTMnet Report for Q92624 (APPBP2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q92624 / APBP2_HUMAN
Protein Name Amyloid protein-binding protein 2
Gene Name Name: APPBP2
Synonyms:KIAA0228;
Organism Homo sapiens (Human)

PRO ID PR:Q92624
DAG View
PRO Name amyloid protein-binding protein 2 (human)
Definition An amyloid protein-binding protein 2 that is encoded in the genome of human.
Short Label hAPPBP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q92624 (APPBP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K68 Methylation PhosphoSitePlus
K68 Ubiquitination PhosphoSitePlus
S106 Phosphorylation PhosphoSitePlus
K178 Ubiquitination PhosphoSitePlus
K187 Ubiquitination PhosphoSitePlus
K195 Ubiquitination PhosphoSitePlus
K198 Ubiquitination PhosphoSitePlus
T237 Phosphorylation PhosphoSitePlus
K254 Ubiquitination PhosphoSitePlus
C256 Methylation IEDB 31844290
K264 Ubiquitination PhosphoSitePlus
K283 Ubiquitination PhosphoSitePlus
K349 Ubiquitination PhosphoSitePlus
K379 Ubiquitination PhosphoSitePlus
K396 Ubiquitination PhosphoSitePlus
K418 Ubiquitination PhosphoSitePlus
K419 Ubiquitination PhosphoSitePlus
K430 Ubiquitination PhosphoSitePlus
K446 Ubiquitination PhosphoSitePlus
K454 Ubiquitination PhosphoSitePlus
K504 Ubiquitination PhosphoSitePlus
Y517 Phosphorylation PhosphoSitePlus
K522 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K68 E68 Biomuta DOID:3571 / liver cancer [ cosmic ]
K178 R178 Biomuta DOID:10283 / prostate cancer [ cosmic ]
T237 I237 Biomuta DOID:263 / kidney cancer [ cosmic ]
C256 S256 Biomuta DOID:1324 / lung cancer [ cosmic ]
K264 N264 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K283 T283 Biomuta DOID:363 / uterine cancer [ icgc ]