iPTMnet Report for Q92615 (LARP4B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q92615 / LAR4B_HUMAN
Protein Name La-related protein 4B
Gene Name Name: LARP4B
Synonyms:KIAA0217,LARP5;
Organism Homo sapiens (Human)

PRO ID PR:Q92615
DAG View
PRO Name La-related protein 4B (human)
Definition A La-related protein 4B that is encoded in the genome of human.
Short Label hLARP4B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q92615 (LARP4B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
Y134 Phosphorylation PhosphoSitePlus
S136 Phosphorylation PhosphoSitePlus
K162 Ubiquitination PhosphoSitePlus
Y188 Phosphorylation PhosphoSitePlus
K201 Ubiquitination PhosphoSitePlus
K202 Ubiquitination PhosphoSitePlus
K225 Ubiquitination PhosphoSitePlus
K228 Ubiquitination PhosphoSitePlus
S244 Phosphorylation PhosphoSitePlus
T247 Phosphorylation PhosphoSitePlus
K257 Ubiquitination PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
K302 Ubiquitination PhosphoSitePlus
K305 Ubiquitination PhosphoSitePlus
K311 Ubiquitination PhosphoSitePlus
K321 Ubiquitination PhosphoSitePlus
S330 Phosphorylation PhosphoSitePlus
Y332 Phosphorylation PhosphoSitePlus
T389 Phosphorylation HPRD 20068231
S398 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 20068231, 18220336
R404 Methylation PhosphoSitePlus   UniProt 24129315
S414 Phosphorylation PhosphoSitePlus
K415 Ubiquitination PhosphoSitePlus
R419 Methylation PhosphoSitePlus   UniProt 24129315
S424 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
R427 Methylation PhosphoSitePlus
S434 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17924679, 16964243, ...18220336
S436 Phosphorylation PhosphoSitePlus
R444 Methylation PhosphoSitePlus
S451 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
R463 Methylation PhosphoSitePlus
S468 Phosphorylation PhosphoSitePlus
Y470 Phosphorylation PhosphoSitePlus
K472 Methylation PhosphoSitePlus
S488 Phosphorylation PhosphoSitePlus   UniProt 23186163
R493 Methylation PhosphoSitePlus
R495 Methylation PhosphoSitePlus
S498 Phosphorylation HPRD   PhosphoSitePlus 18212344, 20068231
Y501 Phosphorylation PhosphoSitePlus
T510 Phosphorylation HPRD   PhosphoSitePlus 17081983, 20068231
S511 Phosphorylation PhosphoSitePlus
S512 Phosphorylation HPRD   phospho.ELM 18669648
T514 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 17081983
S516 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 20068231
T518 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
S524 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332, ...20068231
S526 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 17081983
S532 Phosphorylation HPRD   phospho.ELM 18669648, 17081983
S533 Phosphorylation HPRD 17081983
R553 Methylation PhosphoSitePlus
S556 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 18212344, 20068231
K563 Ubiquitination PhosphoSitePlus
T566 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 16964243, 20068231
S568 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 18220336
S572 Phosphorylation PhosphoSitePlus
S581 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...30059200, 28657654, 35254053, 34019948, 31492838, 32119511, 28510447, 34229054, 29237092
S585 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...32938750, 30059200, 28657654, 35254053, 34019948, 31492838, 32119511, 28510447, 34229054, 29237092
S585 Phosphorylation PhosphoSitePlus
S589 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...32938750, 30059200, 28657654, 35254053, 34019948, 31492838, 32119511, 28510447, 34229054, 29237092
S589 Phosphorylation PhosphoSitePlus
S593 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...30059200, 28657654, 35254053, 34019948, 31492838, 32119511, 28510447, 34229054, 29237092
S593 Phosphorylation HPRD   PhosphoSitePlus 20068231
T595 Phosphorylation HPRD   PhosphoSitePlus 20068231
Y596 Phosphorylation HPRD   PhosphoSitePlus 20068231
S599 Phosphorylation HPRD   PhosphoSitePlus 19651622, 20068231, 18691976
S601 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 17081983, ...18767875, 19651622, 18669648, 24275569, 18707149, 20068231
S620 Phosphorylation PhosphoSitePlus
R623 Methylation PhosphoSitePlus
S626 Phosphorylation PhosphoSitePlus
T629 Phosphorylation PhosphoSitePlus
S635 Phosphorylation PhosphoSitePlus
T643 Phosphorylation PhosphoSitePlus
K647 Ubiquitination PhosphoSitePlus
S649 Phosphorylation PhosphoSitePlus
Y650 Phosphorylation PhosphoSitePlus
S663 Phosphorylation HPRD   PhosphoSitePlus 19413330
S664 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 23186163
T676 Phosphorylation PhosphoSitePlus
Y693 Phosphorylation PhosphoSitePlus
S701 Phosphorylation PhosphoSitePlus
T702 Phosphorylation PhosphoSitePlus
S718 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 17081983, 20068231
S720 Phosphorylation HPRD   PhosphoSitePlus 20068231
K724 Acetylation PhosphoSitePlus   UniProt 19608861
S727 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18669648, 20068231
S731 Phosphorylation HPRD   PhosphoSitePlus 17081983, 20068231
T732 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19413330, 17081983, 19651622, ...18669648, 20068231
S736 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 17081983, 19651622, ...18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S136 C136 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K201 N201 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K225 N225 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K302 N302 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K305 N305 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K321 N321 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
T389 M389 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
R419 L419 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
R444 L444 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R444 Q444 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
R444 * Biomuta DOID:4159 / skin cancer [ cosmic, tcga ]
S451 C451 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
R463 Q463 Biomuta DOID:1319 / brain cancer [ cosmic ]
S498 F498 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ]
Y501 N501 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S511 N511 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S526 R526 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S533 G533 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S533 R533 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S568 N568 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S581 F581 Biomuta DOID:4159 / skin cancer [ cosmic ]
S585 L585 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S589 F589 Biomuta DOID:4159 / skin cancer [ cosmic ]
S593 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
Y596 C596 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S599 P599 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S635 A635 Biomuta DOID:3571 / liver cancer [ cosmic ]
T643 M643 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y693 N693 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
Y693 C693 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S720 L720 Biomuta DOID:363 / uterine cancer [ icgc ]
S731 N731 Biomuta DOID:9256 / colorectal cancer [ cosmic ]