iPTMnet Report for Q92599 (SEPTIN8)
Protein Information
| UniProt AC / UniProt ID | Q92599 / SEPT8_HUMAN |
| Protein Name | Septin-8 |
| Gene Name | Name: SEPTIN8 Synonyms:KIAA0202; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q92599 |
| PRO Name | septin-8 (human) |
| Definition | A septin-8 that is encoded in the genome of human. |
| Short Label | hSEPTIN8 |
| Category | organism-gene |
DAG ViewQ92599 (SEPTIN8) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 22814378 | ||
| T4 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S10 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| R17 | Methylation | score1 | PhosphoSitePlus | |||
| S20 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S29 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S36 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C80 | Methylation | score1 | IEDB | 31844290 | ||
| T100 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S141 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C153 | Methylation | score1 | IEDB | 31844290 | ||
| S163 | Phosphorylation | score2 | PhosphoSitePlus | 22649572 | ||
| S163 | Phosphorylation | Q8IW41 (MAPKAPK5) | score2 | PhosphoSitePlus | 22649572 | |
| K173 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K178 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S192 | Phosphorylation | score2 | PhosphoSitePlus | 22649572 | ||
| S192 | Phosphorylation | Q8IW41 (MAPKAPK5) | score2 | PhosphoSitePlus | 22649572 | |
| K193 | Acetylation | score1 | PhosphoSitePlus | |||
| K193 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K198 | Acetylation | score1 | PhosphoSitePlus | |||
| K198 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K200 | Acetylation | score1 | PhosphoSitePlus | |||
| K251 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y297 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y300 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K304 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S313 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S321 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y326 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K329 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K331 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K340 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K351 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K353 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K360 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K369 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K381 | Acetylation | score1 | PhosphoSitePlus | |||
| K387 | Acetylation | score1 | PhosphoSitePlus | |||
| K402 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T416 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S20 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S435 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S438 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T440 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| R17 | W17 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S20 | P20 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| S20 | Y20 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| S36 | N36 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc, cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic, cosmic ] | |
| S36 | C36 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S141 | L141 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| K193 | N193 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| S321 | T321 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
