iPTMnet Report for Q92565 (RAPGEF5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q92565 / RPGF5_HUMAN
Protein Name Rap guanine nucleotide exchange factor 5
Gene Name Name: RAPGEF5
Synonyms:GFR,KIAA0277,MRGEF;
Organism Homo sapiens (Human)

PRO ID PR:Q92565
DAG View
PRO Name Rap guanine nucleotide exchange factor 5 (human)
Definition A Rap guanine nucleotide exchange factor 5 that is encoded in the genome of human.
Short Label hRAPGEF5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q92565 (RAPGEF5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y70 Phosphorylation PhosphoSitePlus
S74 Phosphorylation PhosphoSitePlus
T76 Phosphorylation PhosphoSitePlus
Y126 Phosphorylation PhosphoSitePlus
S127 Phosphorylation PhosphoSitePlus
K191 Acetylation PhosphoSitePlus
T207 Phosphorylation PhosphoSitePlus
Y211 Phosphorylation PhosphoSitePlus
S212 Phosphorylation PhosphoSitePlus
S225 Phosphorylation PhosphoSitePlus
S471 Phosphorylation PhosphoSitePlus
S555 Phosphorylation PhosphoSitePlus
S573 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S74 F74 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K191 N191 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S212 P212 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]