iPTMnet Report for Q92562 (FIG4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q92562 / FIG4_HUMAN
Protein Name Polyphosphoinositide phosphatase
Gene Name Name: FIG4
Synonyms:KIAA0274,SAC3;
Organism Homo sapiens (Human)

PRO ID PR:Q92562
DAG View
PRO Name polyphosphoinositide phosphatase (human)
Definition A polyphosphoinositide phosphatase that is encoded in the genome of human.
Short Label hFIG4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q92562 (FIG4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K35 Ubiquitination PhosphoSitePlus
K47 Ubiquitination PhosphoSitePlus
R55 Methylation PhosphoSitePlus
K81 Ubiquitination PhosphoSitePlus
Y125 Phosphorylation PhosphoSitePlus
K190 Ubiquitination PhosphoSitePlus
Y263 Phosphorylation PhosphoSitePlus
Y268 Phosphorylation PhosphoSitePlus
K379 Ubiquitination PhosphoSitePlus
K425 Ubiquitination PhosphoSitePlus
K559 Ubiquitination PhosphoSitePlus
S630 Phosphorylation PhosphoSitePlus
Y631 Phosphorylation PhosphoSitePlus
K704 Ubiquitination PhosphoSitePlus
S724 O-Glycosylation GlyGen 30620550
K780 Acetylation PhosphoSitePlus
S787 Phosphorylation PhosphoSitePlus
K830 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R55 M55 Biomuta DOID:363 / uterine cancer [ icgc ]
K379 N379 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K780 N780 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S787 N787 Biomuta DOID:9256 / colorectal cancer [ cosmic ]