iPTMnet Report for Q92551 (IP6K1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q92551 / IP6K1_HUMAN
Protein Name Inositol hexakisphosphate kinase 1
Gene Name Name: IP6K1
Synonyms:IHPK1,KIAA0263;
Organism Homo sapiens (Human)

PRO ID PR:Q92551
DAG View
PRO Name inositol hexakisphosphate kinase 1 (human)
Definition An inositol hexakisphosphate kinase 1 that is encoded in the genome of human.
Short Label hIP6K1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q92551 (IP6K1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K49 Ubiquitination PhosphoSitePlus
S118 Phosphorylation PhosphoSitePlus
S121 Phosphorylation PhosphoSitePlus
S125 Phosphorylation PhosphoSitePlus
S127 Phosphorylation PhosphoSitePlus
S137 Phosphorylation PhosphoSitePlus
S139 Phosphorylation PhosphoSitePlus
T142 Phosphorylation PhosphoSitePlus
S143 Phosphorylation PhosphoSitePlus
S145 Phosphorylation PhosphoSitePlus
S146 Phosphorylation PhosphoSitePlus
K150 Ubiquitination PhosphoSitePlus
S151 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
K177 Ubiquitination PhosphoSitePlus
S184 Phosphorylation PhosphoSitePlus
K189 Ubiquitination PhosphoSitePlus
S199 Phosphorylation PhosphoSitePlus
C221 Methylation IEDB 31844290
Y331 Phosphorylation PhosphoSitePlus
C344 Methylation IEDB 31844290
S377 Phosphorylation PhosphoSitePlus
Y422 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S151 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K49 E49 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S121 R121 Biomuta DOID:1612 / breast cancer [ cosmic ]
S121 N121 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K150 N150 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K189 T189 Biomuta DOID:9256 / colorectal cancer [ cosmic ]