iPTMnet Report for Q92539 (LPIN2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q92539 / LPIN2_HUMAN
Protein Name Phosphatidate phosphatase LPIN2
Gene Name Name: LPIN2
Synonyms:KIAA0249;
Organism Homo sapiens (Human)

PRO ID PR:Q92539
DAG View
PRO Name phosphatidate phosphatase LPIN2 (human)
Definition A phosphatidate phosphatase LPIN2 that is encoded in the genome of human.
Short Label hLPIN2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q92539 (LPIN2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T92 Phosphorylation PhosphoSitePlus
T105 Phosphorylation PhosphoSitePlus
S106 Phosphorylation HPRD   PRO   PhosphoSitePlus   UniProt 19413330, 23186163, 20068231, ...20058876
T120 Phosphorylation PhosphoSitePlus
S125 Phosphorylation PhosphoSitePlus
T180 Phosphorylation PhosphoSitePlus
S186 Phosphorylation PhosphoSitePlus
S187 Phosphorylation PhosphoSitePlus
S203 Phosphorylation PhosphoSitePlus
S224 Phosphorylation PhosphoSitePlus
S229 Phosphorylation PhosphoSitePlus
S243 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18088087, 23186163, 17081983, ...19651622
S245 Phosphorylation HPRD   PhosphoSitePlus 19651622, 20068231
S254 Phosphorylation PhosphoSitePlus
T291 Phosphorylation PhosphoSitePlus
S303 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20058876, 23186163
K393 Ubiquitination PhosphoSitePlus
S395 Phosphorylation PhosphoSitePlus
Y404 Phosphorylation PhosphoSitePlus
K409 Ubiquitination PhosphoSitePlus
S425 Phosphorylation PhosphoSitePlus
Y515 Phosphorylation PhosphoSitePlus
Y518 Phosphorylation PhosphoSitePlus
Y519 Phosphorylation PhosphoSitePlus
S566 Phosphorylation PhosphoSitePlus   UniProt 24275569
T568 Phosphorylation PhosphoSitePlus
S574 Phosphorylation PhosphoSitePlus
S604 Phosphorylation PhosphoSitePlus
S605 Phosphorylation PhosphoSitePlus
S606 Phosphorylation PhosphoSitePlus
K781 Ubiquitination PhosphoSitePlus
S865 Phosphorylation PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048237 (hLPIN2/Phos:1) pS106 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S125 L125 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S229 P229 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S245 L245 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S425 L425 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
Y519 C519 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K781 N781 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]