iPTMnet Report for Q92530 (PSMF1)
Protein Information
UniProt AC / UniProt ID | Q92530 / PSMF1_HUMAN |
Protein Name | Proteasome inhibitor PI31 subunit |
Gene Name | Name: PSMF1 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q92530 |
PRO Name | proteasome inhibitor PI31 subunit (human) |
Definition | A proteasome inhibitor PI31 subunit that is encoded in the genome of human. |
Short Label | hPSMF1 |
Category | organism-gene |
Q92530 (PSMF1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 22223895, 25944712 | ||
C17 | Methylation | score1 | IEDB | 31844290 | ||
C24 | Methylation | score1 | IEDB | 31844290 | ||
K50 | Ubiquitination | score1 | PhosphoSitePlus | |||
K125 | Ubiquitination | score1 | PhosphoSitePlus | |||
S136 | Phosphorylation | score1 | PhosphoSitePlus | |||
T140 | Phosphorylation | score1 | PhosphoSitePlus | |||
K148 | Ubiquitination | score1 | PhosphoSitePlus | |||
S152 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 18669648, 20068231 | ||
S153 | Phosphorylation | score4 | HPRD PhosphoSitePlus RLIMS-P UniProt | 23186163, 18767875, 17322306, ... | ||
R204 | Methylation | score1 | PhosphoSitePlus | |||
R205 | Methylation | score1 | PhosphoSitePlus | |||
R214 | Methylation | score1 | PhosphoSitePlus | |||
R219 | Methylation | score1 | PhosphoSitePlus | |||
R231 | Methylation | score2 | PhosphoSitePlus UniProt | 24129315 | ||
T251 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 18669648 | ||
S252 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 18669648, 19690332, 20068231 | ||
Y266 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y270 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K125 | R125 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
S136 | P136 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S153 | I153 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
R204 | W204 | Biomuta | DOID:1793 / pancreatic cancer [ icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
R204 | Q204 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] |