iPTMnet Report for Q92529 (SHC3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q92529 / SHC3_HUMAN
Protein Name SHC-transforming protein 3
Gene Name Name: SHC3
Synonyms:NSHC,SHCC;
Organism Homo sapiens (Human)

PRO ID PR:Q92529
DAG View
PRO Name SHC-transforming protein 3 (human)
Definition An SHC-transforming protein 3 that is encoded in the genome of human.
Short Label hSHC3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q92529 (SHC3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Phosphorylation PRO
Y46 Phosphorylation PhosphoSitePlus
S210 Phosphorylation PhosphoSitePlus
S224 Phosphorylation PhosphoSitePlus
Y308 Phosphorylation PhosphoSitePlus
S337 Phosphorylation PhosphoSitePlus
Y341 Phosphorylation PhosphoSitePlus
Y342 Phosphorylation PhosphoSitePlus
S344 Phosphorylation PhosphoSitePlus
Y379 Phosphorylation PhosphoSitePlus
Y380 Phosphorylation PhosphoSitePlus
Y406 Phosphorylation PhosphoSitePlus
S407 Phosphorylation PhosphoSitePlus
Y424 Phosphorylation PhosphoSitePlus
S474 Phosphorylation PhosphoSitePlus
S479 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T22 Phosphorylation PhosphoSitePlus
Y218 Phosphorylation P12931 (SRC) , P00533 (EGFR) , Q16620 (NTRK2) , P04629 (NTRK1) neXtProt   PhosphoSitePlus 11791173
Y219 Phosphorylation Q16620 (NTRK2) , P12931 (SRC) , P00533 (EGFR) , P04629 (NTRK1) neXtProt   PhosphoSitePlus 11791173
Y256 Phosphorylation Q16620 (NTRK2) , P12931 (SRC) , P04629 (NTRK1) , P00533 (EGFR) neXtProt   PhosphoSitePlus 11791173
Y257 Phosphorylation P04629 (NTRK1) , Q16620 (NTRK2) , P12931 (SRC) , P00533 (EGFR) neXtProt   PhosphoSitePlus 11791173
Y283 Phosphorylation Q16620 (NTRK2) , P04629 (NTRK1) , P00533 (EGFR) , P12931 (SRC) neXtProt   PhosphoSitePlus 11791173
Y301 Phosphorylation P04629 (NTRK1) , P00533 (EGFR) , P12931 (SRC) , Q16620 (NTRK2) neXtProt   PhosphoSitePlus 11791173


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000049235 (hSHC3/PhosTyr+) p PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S210 C210 Biomuta DOID:1324 / lung cancer [ cosmic ]
S224 N224 Biomuta DOID:1324 / lung cancer [ cosmic ]
S407 T407 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]