iPTMnet Report for Q92519 (TRIB2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q92519 / TRIB2_HUMAN
Protein Name Tribbles homolog 2
Gene Name Name: TRIB2
Synonyms:TRB2;
Organism Homo sapiens (Human)

PRO ID PR:Q92519
DAG View
PRO Name tribbles homolog 2 (human)
Definition A tribbles homolog 2 that is encoded in the genome of human.
Short Label hTRIB2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q92519 (TRIB2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y14 Phosphorylation PhosphoSitePlus
K20 Ubiquitination PhosphoSitePlus
S28 Phosphorylation PhosphoSitePlus
S29 Phosphorylation PhosphoSitePlus
S83 Phosphorylation P23443 (RPS6KB1) PhosphoSitePlus   RLIMS-P 24089522
S133 Phosphorylation PhosphoSitePlus
Y134 Phosphorylation PhosphoSitePlus
S139 Phosphorylation PhosphoSitePlus
T143 Phosphorylation PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
Y218 Phosphorylation PhosphoSitePlus
T298 Phosphorylation PhosphoSitePlus
S299 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y14 N14 Biomuta DOID:4159 / skin cancer [ cosmic ]
S139 F139 Biomuta DOID:1324 / lung cancer [ cosmic ]
K192 N192 Biomuta DOID:3571 / liver cancer [ cosmic ]
S299 L299 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S299 A299 Biomuta DOID:10534 / stomach cancer [ cosmic ]