iPTMnet Report Q92484 SMPDL3A

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q92484 / ASM3A_HUMAN
Protein Name	Acid sphingomyelinase-like phosphodiesterase 3a precursor
Gene Name	Name: SMPDL3A Synonyms:ASML3A;
Organism	Homo sapiens (Human)

PRO ID	PR:Q92484 DAG View
PRO Name	acid sphingomyelinase-like phosphodiesterase 3a (human)
Definition	An acid sphingomyelinase-like phosphodiesterase 3a that is encoded in the genome of human.
Short Label	hSMPDL3A
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q92484 (SMPDL3A) as Substrate

Condensed View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	N69	N-Glycosylation		score4	GlyGen UniProt	28104755, 26783088
	N131	N-Glycosylation		score3	GlyGen UniProt	26783088
	N222	N-Glycosylation		score4	GlyGen UniProt	28104755, 19159218
	N263	N-Glycosylation		score2	GlyGen UniProt	23090970, 29741879, 19159218, ...24190977
	Y291	Phosphorylation		score1	PhosphoSitePlus
	N356	N-Glycosylation		score4	GlyGen UniProt	26783088, 28104755, 29671580, ...19159218
	Y372	Phosphorylation		score1	PhosphoSitePlus
	T377	Phosphorylation		score1	PhosphoSitePlus
	Y378	Phosphorylation		score2	IEDB PhosphoSitePlus	35494241

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	N356	N-Glycosylation		score1	PRO	29671580

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
N69	D69	Biomuta		DOID:9256 / colorectal cancer [ cosmic ]