iPTMnet Report for Q923E4 (Sirt1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q923E4 / SIR1_MOUSE
Protein Name NAD-dependent protein deacetylase sirtuin-1
Gene Name Name: Sirt1
Synonyms:Sir2l1;
Organism Mus musculus (Mouse)

PRO ID PR:Q923E4
DAG View
PRO Name NAD-dependent protein deacetylase sirtuin-1 (mouse)
Definition An NAD-dependent protein deacetylase sirtuin-1 that is encoded in the genome of mouse.
Short Label mSIRT1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q923E4 (Sirt1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S14 Phosphorylation PhosphoSitePlus
S16 Phosphorylation PhosphoSitePlus
S46 Phosphorylation Q91Y86 (Mapk8) PhosphoSitePlus 21540183
S51 Phosphorylation PhosphoSitePlus
T146 Phosphorylation PhosphoSitePlus
S151 Phosphorylation PhosphoSitePlus   UniProt 21183079
S154 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 21183079, 19680552, 27470296
S164 Phosphorylation PhosphoSitePlus   RLIMS-P 28533219
K230 Acetylation UniProt 28923965
K369 Acetylation UniProt 28923965
C387 S-Nitrosylation dbSNO 20972425
C390 S-Nitrosylation dbSNO 20972425
K422 Acetylation UniProt 28923965
S434 Phosphorylation PhosphoSitePlus   RLIMS-P 22195961
K505 Acetylation UniProt 28923965
T522 Phosphorylation PhosphoSitePlus   UniProt 20167603
S527 Phosphorylation PhosphoSitePlus
S530 Phosphorylation PhosphoSitePlus
S531 Phosphorylation PhosphoSitePlus
S532 Phosphorylation PhosphoSitePlus
K600 Acetylation UniProt 28923965
S649 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 19680552
S651 Phosphorylation PhosphoSitePlus   RLIMS-P 19680552
S683 Phosphorylation PhosphoSitePlus   RLIMS-P 19680552
Site PTM Type PTM Enzyme Score Source PMID
T522 Phosphorylation PRO 28364022


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000050034 (mSIRT1/iso:m1/Phos:1) pT522 PRO 28364022