Protein Information

Cytoscape View


UniProt AC / UniProt ID Q91Y86 / MK08_MOUSE
Protein Name Mitogen-activated protein kinase 8
Gene Name Name: Mapk8
Synonyms:Jnk1,Prkm8;
Organism Mus musculus (Mouse)

PRO ID PR:Q91Y86
DAG View
PRO Name mitogen-activated protein kinase 8 (mouse)
Definition A mitogen-activated protein kinase 8 that is encoded in the genome of mouse.
Short Label mMAPK8
Category organism-gene

Interactive Sequence View

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Q91Y86 (Mapk8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S129 Phosphorylation P28867 (Prkcd) phospho.ELM   PhosphoSitePlus   RLIMS-P 16483929, 16061178
K153 Ubiquitination PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
T178 Phosphorylation PhosphoSitePlus
S179 Phosphorylation PhosphoSitePlus
T183 Phosphorylation P47809 (Map2k4) phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 30210577, 29085990, 23697951, ...27959936, 24976766, 31514083, 22539006, 32456175, 33303737, 20070884, 29323338, 31419957, 33128669, 25594179, 31482248, 21479164, 17709198, 30853885, 11562351, 19696185, 15345747, 28632169, 24733548, 29433359, 31202835, 28874678
Y185 Phosphorylation P47809 (Map2k4) phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 30210577, 33128669, 16504051, ...29433422, 27959936, 24976766, 31514083, 22539006, 32456175, 33303737, 20070884, 29323338, 31419957, 29085990, 25594179, 31482248, 23697951, 21479164, 17709198, 30853885, 11562351, 19696185, 15345747, 28632169, 24733548, 29433359, 31202835, 28874678
T188 Phosphorylation PhosphoSitePlus
S307 Phosphorylation RLIMS-P 21447485, 19696185, 29433422, ...25381390, 23667647
K308 Acetylation PhosphoSitePlus
S377 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15345747


Q91Y86 (Mapk8) as PTM Enzyme



Substrate Site Score Source PMID
O54918 (Bcl2l11) S55 phospho.ELM 12818176
O54918 (Bcl2l11) S65 phospho.ELM   PhosphoSitePlus 12818176
O54918 (Bcl2l11) S73 phospho.ELM 12818176
O54918 (Bcl2l11) T112 PhosphoSitePlus 18498746
O88809 (Dcx) S332 PhosphoSitePlus 20715151
P01108 (Myc) S62 RLIMS-P+ 10551811
P01108 (Myc) S71 RLIMS-P+ 10551811
P05627 (Jun) S63 PhosphoSitePlus 15350216, 19822666, 12881422, ...18316603, 11896587
P05627 (Jun) S73 PhosphoSitePlus 12881422
P05627 (Jun) T91 PhosphoSitePlus 18316603, 12881422
P05627 (Jun) T93 PhosphoSitePlus 18316603, 12881422
P10417 (Bcl2) S70 phospho.ELM 11323415
P16951 (Atf2) T51 PhosphoSitePlus 16601071
P16951 (Atf2) T53 PhosphoSitePlus 15350216
P28700 (Rxra) S61 PhosphoSitePlus 10383391
P28700 (Rxra) S75 PhosphoSitePlus 10383391
P28700 (Rxra) T87 PhosphoSitePlus 10383391
P28700 (Rxra) S265 PhosphoSitePlus 10383391
P35569 (Irs1) S307 PhosphoSitePlus 15143153
P41971 (Elk3) S359 phospho.ELM   PhosphoSitePlus 11042694
P41971 (Elk3) S365 phospho.ELM   PhosphoSitePlus 11042694
P42225 (Stat1) S727 PhosphoSitePlus 14963018
P42227 (Stat3) S727 PhosphoSitePlus 11553624
P55821 (Stmn2) S62 PhosphoSitePlus 21297631
P55821 (Stmn2) S73 PhosphoSitePlus 21297631, 16618812
P97875 (Jdp2) T148 PhosphoSitePlus 11602244
Q61337 (Bad) S112 PhosphoSitePlus 11983683
Q61337 (Bad) S128 phospho.ELM   PhosphoSitePlus 12189144
Q61337 (Bad) T201 phospho.ELM   PhosphoSitePlus 14967141
Q8C863 (Itch) S199 phospho.ELM 16446428
Q8C863 (Itch) T222 phospho.ELM 16446428
Q8C863 (Itch) S232 phospho.ELM 16446428
Q923E4 (Sirt1) S46 PhosphoSitePlus 21540183