iPTMnet Report for Q8WZA2 (RAPGEF4)
Protein Information
| UniProt AC / UniProt ID | Q8WZA2 / RPGF4_HUMAN |
| Protein Name | Rap guanine nucleotide exchange factor 4 |
| Gene Name | Name: RAPGEF4 Synonyms:CGEF2,EPAC2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8WZA2 |
| PRO Name | Rap guanine nucleotide exchange factor 4 (human) |
| Definition | A Rap guanine nucleotide exchange factor 4 that is encoded in the genome of human. |
| Short Label | hRAPGEF4 |
| Category | organism-gene |
DAG ViewQ8WZA2 (RAPGEF4) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T121 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y150 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y153 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S216 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K645 | Acetylation | score1 | PhosphoSitePlus | |||
| T809 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T810 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y857 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y986 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T809 | A809 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] |
