iPTMnet Report for Q8WZ74 (CTTNBP2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WZ74 / CTTB2_HUMAN
Protein Name Cortactin-binding protein 2
Gene Name Name: CTTNBP2
Synonyms:C7orf8,CORTBP2,KIAA1758;
Organism Homo sapiens (Human)

PRO ID PR:Q8WZ74
DAG View
PRO Name cortactin-binding protein 2 (human)
Definition A cortactin-binding protein 2 that is encoded in the genome of human.
Short Label hCTTNBP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WZ74 (CTTNBP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S126 Phosphorylation PhosphoSitePlus
S134 Phosphorylation PhosphoSitePlus
S220 Phosphorylation HPRD   PhosphoSitePlus 18491316
T221 Phosphorylation HPRD   PhosphoSitePlus 18491316
K264 Acetylation PhosphoSitePlus
K270 Acetylation PhosphoSitePlus
S273 Phosphorylation PhosphoSitePlus
S361 Phosphorylation PhosphoSitePlus
C432 Methylation IEDB 31844290
S436 O-Glycosylation GlyGen 29351928
S475 Phosphorylation PhosphoSitePlus
T500 Phosphorylation PhosphoSitePlus
S501 Phosphorylation PhosphoSitePlus
S508 Phosphorylation PhosphoSitePlus
T520 Phosphorylation PhosphoSitePlus
S557 Phosphorylation PhosphoSitePlus
S1178 Phosphorylation PhosphoSitePlus
T1481 O-Glycosylation GlyGen 29351928
S1505 Phosphorylation PhosphoSitePlus
S1524 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 19664994, 21406692, ...23186163
S1542 Phosphorylation PhosphoSitePlus
S1632 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S134 I134 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S220 R220 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S220 G220 Biomuta DOID:184 / bone cancer [ cosmic ]
S220 I220 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S475 * Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S557 Y557 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T1481 A1481 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1505 Y1505 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S1542 C1542 Biomuta DOID:9256 / colorectal cancer [ cosmic ]