iPTMnet Report for Q8WZ60 (KLHL6)
Protein Information
UniProt AC / UniProt ID | Q8WZ60 / KLHL6_HUMAN |
Protein Name | Kelch-like protein 6 |
Gene Name | Name: KLHL6 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8WZ60 |
PRO Name | kelch-like protein 6 (human) |
Definition | A kelch-like protein 6 that is encoded in the genome of human. |
Short Label | hKLHL6 |
Category | organism-gene |
Q8WZ60 (KLHL6) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K18 | Ubiquitination | score1 | PhosphoSitePlus | |||
S19 | Phosphorylation | score1 | PhosphoSitePlus | |||
K34 | Ubiquitination | score1 | PhosphoSitePlus | |||
K46 | Ubiquitination | score1 | PhosphoSitePlus | |||
K48 | Ubiquitination | score1 | PhosphoSitePlus | |||
S55 | Phosphorylation | score1 | PhosphoSitePlus | |||
T64 | Phosphorylation | score1 | PhosphoSitePlus | |||
C77 | Methylation | score1 | IEDB | 31844290 | ||
K108 | Acetylation | score1 | PhosphoSitePlus | |||
K116 | Ubiquitination | score1 | PhosphoSitePlus | |||
K134 | Ubiquitination | score1 | PhosphoSitePlus | |||
K139 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y297 | Phosphorylation | score1 | PhosphoSitePlus | |||
S300 | Phosphorylation | score1 | PhosphoSitePlus | |||
C339 | Methylation | score1 | IEDB | 31844290 | ||
K352 | Ubiquitination | score1 | PhosphoSitePlus | |||
K385 | Ubiquitination | score1 | PhosphoSitePlus | |||
K393 | Ubiquitination | score1 | PhosphoSitePlus | |||
C447 | Methylation | score1 | IEDB | 31844290 | ||
K485 | Ubiquitination | score1 | PhosphoSitePlus | |||
K495 | Ubiquitination | score1 | PhosphoSitePlus | |||
K499 | Ubiquitination | score1 | PhosphoSitePlus | |||
K507 | Ubiquitination | score1 | PhosphoSitePlus | |||
C508 | Methylation | score1 | IEDB | 31844290 | ||
C539 | Methylation | score1 | IEDB | 31844290 | ||
C556 | Methylation | score1 | IEDB | 31844290 | ||
S597 | Phosphorylation | score1 | IEDB | 35494241 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S55 | C55 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
T64 | A64 | Biomuta | DOID:2394 / ovarian cancer [ cosmic ] | |
T64 | S64 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
T64 | I64 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
C77 | Y77 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
C77 | F77 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
C77 | * | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
K116 | E116 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
C339 | S339 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic ] | |
C339 | Y339 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
C339 | * | Biomuta | [ cosmic ] | |
K485 | N485 | Biomuta | DOID:1793 / pancreatic cancer [ icgc ] | |
K485 | T485 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
C556 | S556 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |